Paraprotein-associated scleroedema (Q106387): Difference between revisions

This form of scleroedema is associated with a monoclonal paraprotein band, usually of IgG kappa type. It may be the harbinger of multiple myeloma and is more likely to affect other organs. It tends to be chronic and progressive. Signs of systemic involvement include enlargement of the tongue and parotid glands, skeletal and cardiac muscle infiltration, and pleural, pericardial and peritoneal effusions.