Pleomorphic xanthoastrocytoma of brain (Q102515): Difference between revisions
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Tumor astrocítico com prognóstico relativamente favorável (OMS grau II), normalmente encontrado em crianças e adultos jovens. Possui localização superficial nos hemisférios cerebrais e envolvimento das meninges. As características incluem células pleomórficas e lipidizadas que expressam GFAP, frequentemente rodeadas por uma rede de reticulina, bem como corpos granulares eosinofílicos. Para lesões com atividade mitótica significativa (5 ou mais mitoses por 10 HPF) e/ou com áreas de necrose, a designação xantoastrocitoma pleomórfico com características anaplásicas pode ser usada. (OMS) | |||
| description / en | description / en | ||
An astrocytic tumour with a relatively favorable prognosis (WHO grade II), typically encountered in children and young adults. It has a superficial location in the cerebral hemispheres and involvement of the meninges. Characteristic features include pleomorphic and lipidized cells expressing GFAP and often surrounded by a reticulin network as well as eosinophilic granular bodies. For lesions with significant mitotic activity (5 or more mitoses per 10 HPF) and/or with areas of necrosis, the designation pleomorphic xanthoastrocytoma with anaplastic features may be used. (WHO) | |||
Revision as of 19:32, 16 August 2026
An astrocytic tumour with a relatively favorable prognosis (WHO grade II), typically encountered in children and young adults. It has a superficial location in the cerebral hemispheres and involvement of the meninges. Characteristic features include pleomorphic and lipidized cells expressing GFAP and often surrounded by a reticulin network as well as eosinophilic granular bodies. For lesions with significant mitotic activity (5 or more mitoses per 10 HPF) and/or with areas of necrosis, the designation pleomorphic xanthoastrocytoma with anaplastic features may be used. (WHO)
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_1033974606 |
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| English | Pleomorphic xanthoastrocytoma of brain |
An astrocytic tumour with a relatively favorable prognosis (WHO grade II), typically encountered in children and young adults. It has a superficial location in the cerebral hemispheres and involvement of the meninges. Characteristic features include pleomorphic and lipidized cells expressing GFAP and often surrounded by a reticulin network as well as eosinophilic granular bodies. For lesions with significant mitotic activity (5 or more mitoses per 10 HPF) and/or with areas of necrosis, the designation pleomorphic xanthoastrocytoma with anaplastic features may be used. (WHO) |
