MODY 3 syndrome (Q102295): Difference between revisions
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Isso se refere a uma forma hereditária de diabetes causada por mutações em um gene autossômico dominante (independente do sexo, ou seja, herdado de qualquer um dos pais), interrompendo a produção de insulina. Causado por mutações do HNF1α gene (um gene homeobox) e representa 30% –70% dos casos de MODY. Tendem a responder às sulfoniluréias e possuem limiar renal baixo para glicose. | |||
| description / en | description / en | ||
This refers to the hereditary form of diabetes caused by mutations in an autosomal dominant gene (sex independent, i.e. inherited from any of the parents) disrupting insulin production. Mutations of the HNF1? gene (a homeobox gene). 30%–70% cases. Tend to be responsive to sulfonylureas. Low renal threshold for glucose. | |||
Revision as of 19:13, 16 August 2026
This refers to the hereditary form of diabetes caused by mutations in an autosomal dominant gene (sex independent, i.e. inherited from any of the parents) disrupting insulin production. Mutations of the HNF1? gene (a homeobox gene). 30%–70% cases. Tend to be responsive to sulfonylureas. Low renal threshold for glucose.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_964882179 |
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| English | MODY 3 syndrome |
This refers to the hereditary form of diabetes caused by mutations in an autosomal dominant gene (sex independent, i.e. inherited from any of the parents) disrupting insulin production. Mutations of the HNF1? gene (a homeobox gene). 30%–70% cases. Tend to be responsive to sulfonylureas. Low renal threshold for glucose. |
