Meningitis due to Streptococcus agalactiae (Q101492): Difference between revisions
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Inflamação da pia-máter e aracnoide e do líquido espinal associada à infecção por S. agalactiae (estreptococos do Grupo B). A infecção geralmente é observada no período neonatal precoce (primeira semana) ou tardio (semanas 2-4). S. agalactiae é a causa mais comum de septicemia e meningite em recém-nascidos. A meningite pode ser difícil de diagnosticar, pois podem ocorrer sinais inespecíficos de uma doença sistêmica com febre, irritabilidade, sonolência, vômitos e convulsões. A rigidez do pescoço pode estar ausente. Abaulamento de fontanela pode estar presente e alertar para uma meningite subjacente. Um alto índice de suspeita e o uso liberal de punção lombar são fundamentais para o diagnóstico precoce. O diagnóstico é confirmado por exame de LCR (líquido cefalorraquidiano), hemocultura e PCR (reação em cadeia da polimerase). O líquido cefalorraquidiano geralmente apresenta uma pressão elevada, uma leucocitose predominantemente neutrofílica (geralmente 1.000 a 10.000 células/ml), um nível elevado de proteínas e e diminuição da glicose. 15% a 30% dos bebês que sobrevivem à meningite apresentam sequelas neurológicas, incluindo cegueira, surdez e deficiência intelectual. | |||
| description / en | description / en | ||
Inflammation of the pia and arachnoid and spinal fluid associated with S. agalactiae (group B streptococcus) infection. The infection is usually seen in the early (first week) or late (weeks 2-4) neonatal period. S. agalactiae is the commonest cause of septicaemia and meningitis in the newborn. Meningitis may be difficult to diagnose as there may be nonspecific signs of a systemic illness with fever, irritability, drowsiness, vomiting, and convulsions. Stiff neck may be absent. A bulging fontanelle may be present and alert to an underlying meningitis. A high index of suspicion and liberal use of lumbar puncture are keys to early diagnosis. Diagnosis is confirmed by CSF (cerebrospinal fluid) examination, blood culture, and PCR (polymerase chain reaction). The spinal fluid usually shows an elevated pressure, a predominantly neutrophilic leukocytosis (usually 1000 – 10 000 cells / ml) an elevated protein level, and a decreased glucose content. 15 – 30 % of infants who survive meningitis show neurological sequelae, including blindness, deafness, and mental retardation. | |||
Revision as of 18:18, 16 August 2026
Inflammation of the pia and arachnoid and spinal fluid associated with S. agalactiae (group B streptococcus) infection. The infection is usually seen in the early (first week) or late (weeks 2-4) neonatal period. S. agalactiae is the commonest cause of septicaemia and meningitis in the newborn. Meningitis may be difficult to diagnose as there may be nonspecific signs of a systemic illness with fever, irritability, drowsiness, vomiting, and convulsions. Stiff neck may be absent. A bulging fontanelle may be present and alert to an underlying meningitis. A high index of suspicion and liberal use of lumbar puncture are keys to early diagnosis. Diagnosis is confirmed by CSF (cerebrospinal fluid) examination, blood culture, and PCR (polymerase chain reaction). The spinal fluid usually shows an elevated pressure, a predominantly neutrophilic leukocytosis (usually 1000 – 10 000 cells / ml) an elevated protein level, and a decreased glucose content. 15 – 30 % of infants who survive meningitis show neurological sequelae, including blindness, deafness, and mental retardation.
| Language | Label | Description | Also known as |
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| default for all languages | ID_2131706649 |
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| English | Meningitis due to Streptococcus agalactiae |
Inflammation of the pia and arachnoid and spinal fluid associated with S. agalactiae (group B streptococcus) infection. The infection is usually seen in the early (first week) or late (weeks 2-4) neonatal period. S. agalactiae is the commonest cause of septicaemia and meningitis in the newborn. Meningitis may be difficult to diagnose as there may be nonspecific signs of a systemic illness with fever, irritability, drowsiness, vomiting, and convulsions. Stiff neck may be absent. A bulging fontanelle may be present and alert to an underlying meningitis. A high index of suspicion and liberal use of lumbar puncture are keys to early diagnosis. Diagnosis is confirmed by CSF (cerebrospinal fluid) examination, blood culture, and PCR (polymerase chain reaction). The spinal fluid usually shows an elevated pressure, a predominantly neutrophilic leukocytosis (usually 1000 – 10 000 cells / ml) an elevated protein level, and a decreased glucose content. 15 – 30 % of infants who survive meningitis show neurological sequelae, including blindness, deafness, and mental retardation. |
