Motor neuron disease in autoimmune disease including increased anti-GMl ganglioside antibody (Q101489): Difference between revisions
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Há uma maior incidência de doença do neurônio motor (DNM) em pacientes com doença autoimune prévia, sugerindo possíveis fatores de risco genéticos ou ambientais compartilhados. Relatórios ocasionais têm documentado a coexistência de DNM com doença autoimune sintomática. A neuropatia motora multifocal (NMM), uma imitação da DNM, pode estar associada a anticorpos anti-gangliosídeos GM1. Os anticorpos anti-gangliosídeos GM1 em baixo título podem ser detectados em pacientes com DNM, sem manifestações clínicas ou neurofisiológicas de NMM. | |||
| description / en | description / en | ||
There is a higher incidence of motor neuron disease (MND) in patients with preceding autoimmune disease, suggesting possible shared genetic or environmental risk factors. Occasional reports have documented the coexistence of MND with symptomatic autoimmune disease. Multifocal motor neuropathy (MMN), a mimic of MND, may be associated with anti GM1 ganglioside antibodies. Low-titre anti-GM1 ganglioside antibodies may be detected in patients with MND, without clinical or neurophysiological features of MMN. | |||
Revision as of 18:18, 16 August 2026
There is a higher incidence of motor neuron disease (MND) in patients with preceding autoimmune disease, suggesting possible shared genetic or environmental risk factors. Occasional reports have documented the coexistence of MND with symptomatic autoimmune disease. Multifocal motor neuropathy (MMN), a mimic of MND, may be associated with anti GM1 ganglioside antibodies. Low-titre anti-GM1 ganglioside antibodies may be detected in patients with MND, without clinical or neurophysiological features of MMN.
| Language | Label | Description | Also known as |
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| default for all languages | ID_955868778 |
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| English | Motor neuron disease in autoimmune disease including increased anti-GMl ganglioside antibody |
There is a higher incidence of motor neuron disease (MND) in patients with preceding autoimmune disease, suggesting possible shared genetic or environmental risk factors. Occasional reports have documented the coexistence of MND with symptomatic autoimmune disease. Multifocal motor neuropathy (MMN), a mimic of MND, may be associated with anti GM1 ganglioside antibodies. Low-titre anti-GM1 ganglioside antibodies may be detected in patients with MND, without clinical or neurophysiological features of MMN. |
