Chronic painful chemotherapy-induced polyneuropathy (Q101432): Difference between revisions

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Polineuropatia dolorosa crônica induzida por quimioterapia (PNIQ) é uma dor neuropática periférica crônica causada por quimioterapia oral ou intravenosa, administrada para tratar um tumor primário ou metástases. A dor pode ser o sintoma inicial de uma neuropatia ou se desenvolver durante o curso da doença. A dor pode ser espontânea ou evocada, como uma resposta aumentada a um estímulo doloroso (hiperalgesia) ou uma resposta dolorosa a um estímulo normalmente não doloroso (alodínia). Sinais ou sintomas sensoriais negativos (p.ex., diminuição ou perda de sensibilidade) e positivos (p.ex., alodínia ou hiperalgesia) devem ser compatíveis com o padrão de distribuição anatômica da polineuropatia.
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Chronic painful chemotherapy-induced polyneuropathy (CIPN) is chronic peripheral neuropathic pain caused by oral or intravenous chemotherapy given to treat the primary tumour or metastases. Pain may be the initial symptom of a neuropathy or develop over the course of the disease. The pain may be spontaneous or evoked, as an increased response to a painful stimulus (hyperalgesia) or a painful response to a normally nonpainful stimulus (allodynia). Negative (e.g., decreased or loss of sensation) and positive sensory symptoms or signs (e.g., allodynia or hyperalgesia) must be compatible with the anatomical distribution pattern of the polyneuropathy.

Revision as of 18:14, 16 August 2026

Chronic painful chemotherapy-induced polyneuropathy (CIPN) is chronic peripheral neuropathic pain caused by oral or intravenous chemotherapy given to treat the primary tumour or metastases. Pain may be the initial symptom of a neuropathy or develop over the course of the disease. The pain may be spontaneous or evoked, as an increased response to a painful stimulus (hyperalgesia) or a painful response to a normally nonpainful stimulus (allodynia). Negative (e.g., decreased or loss of sensation) and positive sensory symptoms or signs (e.g., allodynia or hyperalgesia) must be compatible with the anatomical distribution pattern of the polyneuropathy.
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    Chronic painful chemotherapy-induced polyneuropathy
    Chronic painful chemotherapy-induced polyneuropathy (CIPN) is chronic peripheral neuropathic pain caused by oral or intravenous chemotherapy given to treat the primary tumour or metastases. Pain may be the initial symptom of a neuropathy or develop over the course of the disease. The pain may be spontaneous or evoked, as an increased response to a painful stimulus (hyperalgesia) or a painful response to a normally nonpainful stimulus (allodynia). Negative (e.g., decreased or loss of sensation) and positive sensory symptoms or signs (e.g., allodynia or hyperalgesia) must be compatible with the anatomical distribution pattern of the polyneuropathy.

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