Hereditary nonpolyposis colorectal cancer (Q97091): Difference between revisions
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A síndrome de Lynch (HNPCC ou câncer colorretal hereditário não poliposo) é uma condição genética autossômica dominante que tem um alto risco de câncer do cólon, bem como outros cânceres, incluindo estômago, intestino delgado, fígado, ductos da vesícula biliar, trato urinário superior, cérebro, pele e próstata. Mulheres com esse transtorno também têm um alto risco de câncer do endométrio (revestimento do útero) e ovários. O risco aumentado para esses tipos de câncer se deve a mutações hereditárias que comprometem o reparo de incompatibilidades do DNA. | |||
| description / en | description / en | ||
Lynch syndrome (HNPCC or Hereditary nonpolyposis colorectal cancer) is an autosomal dominant genetic condition which has a high risk of colon cancer as well as other cancers including stomach, small intestine, liver, gallbladder ducts, upper urinary tract, brain, skin, and prostate. Women with this disorder also have a high risk of cancer of the endometrium (lining of the uterus) and ovaries.The increased risk for these cancers is due to inherited mutations that impair DNA mismatch repair. | |||
Revision as of 13:07, 16 August 2026
Lynch syndrome (HNPCC or Hereditary nonpolyposis colorectal cancer) is an autosomal dominant genetic condition which has a high risk of colon cancer as well as other cancers including stomach, small intestine, liver, gallbladder ducts, upper urinary tract, brain, skin, and prostate. Women with this disorder also have a high risk of cancer of the endometrium (lining of the uterus) and ovaries.The increased risk for these cancers is due to inherited mutations that impair DNA mismatch repair.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_8113015 |
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| English | Hereditary nonpolyposis colorectal cancer |
Lynch syndrome (HNPCC or Hereditary nonpolyposis colorectal cancer) is an autosomal dominant genetic condition which has a high risk of colon cancer as well as other cancers including stomach, small intestine, liver, gallbladder ducts, upper urinary tract, brain, skin, and prostate. Women with this disorder also have a high risk of cancer of the endometrium (lining of the uterus) and ovaries.The increased risk for these cancers is due to inherited mutations that impair DNA mismatch repair. |
