Juvenile dermatomyositis with lipodystrophy (Q92505): Difference between revisions
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Dermatomiosite juvenil com lipodistrofia é uma doença autoimune sistêmica crônica caracterizada por fraqueza proximal de início precoce e erupções cutâneas características, associadas à perda de gordura subcutânea em uma distribuição localizada ou generalizada, frequentemente com anormalidades metabólicas resultantes, como resistência à insulina, diabetes e hiperlipidemia. Esses pacientes têm uma perda de adipócitos maduros e funcionais, em oposição à ausência de lipídios em adipócitos normais. | |||
| description / en | description / en | ||
Juvenile dermatomyositis with lipodystrophy is a chronic systemic autoimmune disease characterised by early-onset proximal weakness and characteristic skin rashes, associated with loss of subcutaneous fat in a localised or generalised distribution, frequently with resultant metabolic abnormalities such as insulin resistance, diabetes and hyperlipidaemia. These patients have a loss of mature, functional adipocytes, as opposed to an absence of lipid in otherwise normal adipocytes. | |||
Revision as of 07:38, 16 August 2026
Juvenile dermatomyositis with lipodystrophy is a chronic systemic autoimmune disease characterised by early-onset proximal weakness and characteristic skin rashes, associated with loss of subcutaneous fat in a localised or generalised distribution, frequently with resultant metabolic abnormalities such as insulin resistance, diabetes and hyperlipidaemia. These patients have a loss of mature, functional adipocytes, as opposed to an absence of lipid in otherwise normal adipocytes.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_2133970870 |
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| English | Juvenile dermatomyositis with lipodystrophy |
Juvenile dermatomyositis with lipodystrophy is a chronic systemic autoimmune disease characterised by early-onset proximal weakness and characteristic skin rashes, associated with loss of subcutaneous fat in a localised or generalised distribution, frequently with resultant metabolic abnormalities such as insulin resistance, diabetes and hyperlipidaemia. These patients have a loss of mature, functional adipocytes, as opposed to an absence of lipid in otherwise normal adipocytes. |
