Anti-synthetase syndrome with polymyositis (Q90725): Difference between revisions
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Síndrome antissintetase com polimiosite é uma doença muscular inflamatória associada a autoanticorpos antissintetase, sendo os autoanticorpos anti-Jo-1, o autoanticorpo antissintetase mais comum. Estes pacientes têm uma constelação de sintomas, incluindo mialgias, fraqueza muscular e uma combinação de sintomas “centrais”, incluindo doença pulmonar intersticial, fenômeno de Raynaud, artrite soronegativa das articulações distais, febre, mãos de mecânico e erupção cutânea diferente do eritema heliotrópico observado na dermatomiosite. | |||
| description / en | description / en | ||
Anti-synthetase syndrome with polymyositis is an inflammatory muscle disease associated with antisynthetase autoantibodies, being the anti-Jo-1 autoantibodies the most common anti-synthetase autoantibody. These patients have a constellation of symptoms, including myalgias, muscle weakness, and a combination of “core” symptoms, including interstitial lung disease, Raynaud phenomenon, seronegative arthritis of the distal joints, fever, mechanic’s hands, and a skin rash different from the heliotrope erythema seen in dermatomyositis. | |||
Revision as of 17:42, 15 August 2026
Anti-synthetase syndrome with polymyositis is an inflammatory muscle disease associated with antisynthetase autoantibodies, being the anti-Jo-1 autoantibodies the most common anti-synthetase autoantibody. These patients have a constellation of symptoms, including myalgias, muscle weakness, and a combination of “core” symptoms, including interstitial lung disease, Raynaud phenomenon, seronegative arthritis of the distal joints, fever, mechanic’s hands, and a skin rash different from the heliotrope erythema seen in dermatomyositis.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_1949745299 |
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| English | Anti-synthetase syndrome with polymyositis |
Anti-synthetase syndrome with polymyositis is an inflammatory muscle disease associated with antisynthetase autoantibodies, being the anti-Jo-1 autoantibodies the most common anti-synthetase autoantibody. These patients have a constellation of symptoms, including myalgias, muscle weakness, and a combination of “core” symptoms, including interstitial lung disease, Raynaud phenomenon, seronegative arthritis of the distal joints, fever, mechanic’s hands, and a skin rash different from the heliotrope erythema seen in dermatomyositis. |
