Eccrine syringosquamous metaplasia (Q90209): Difference between revisions
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Siringometaplasia escamosa écrina descreve um achado microscópico distinto de lesão do ducto écrino em que um insulto, mais comumente quimioterapia citotóxica, resultou em uma transformação do epitélio cuboide normal para escamoso, o que pode simular carcinoma de células escamosas. Os pacientes apresentam pápulas eritematosas, frequentemente de distribuição generalizada e às vezes com vesículas e pústulas. Também podem apresentar eritema acral. Drogas implicadas incluem citarabina, doxorrubicina, cisplatina e inibidores de proteína quinase. | |||
| description / en | description / en | ||
Eccrine syringosquamous metaplasia describes a distinctive microscopic finding of eccrine duct damage in which an insult, most commonly cytotoxic chemotherapy, has resulted in a transformation from the normal cuboidal to squamous epithelium, which may simulate squamous cell carcinoma. Patients present with erythematous papules, often in a generalised distribution and sometimes with vesicles and pustules. It may also present with acral erythema. Drugs implicated include cytarabine, doxorubicin, cis-platinum and protein kinase inhibitors. | |||
Revision as of 17:09, 15 August 2026
Eccrine syringosquamous metaplasia describes a distinctive microscopic finding of eccrine duct damage in which an insult, most commonly cytotoxic chemotherapy, has resulted in a transformation from the normal cuboidal to squamous epithelium, which may simulate squamous cell carcinoma. Patients present with erythematous papules, often in a generalised distribution and sometimes with vesicles and pustules. It may also present with acral erythema. Drugs implicated include cytarabine, doxorubicin, cis-platinum and protein kinase inhibitors.
| Language | Label | Description | Also known as |
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| default for all languages | ID_407987403 |
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| English | Eccrine syringosquamous metaplasia |
Eccrine syringosquamous metaplasia describes a distinctive microscopic finding of eccrine duct damage in which an insult, most commonly cytotoxic chemotherapy, has resulted in a transformation from the normal cuboidal to squamous epithelium, which may simulate squamous cell carcinoma. Patients present with erythematous papules, often in a generalised distribution and sometimes with vesicles and pustules. It may also present with acral erythema. Drugs implicated include cytarabine, doxorubicin, cis-platinum and protein kinase inhibitors. |
