Myelopathy due to excess of zinc (Q89797): Difference between revisions
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A mieloneuropatia induzida por zinco foi recentemente (re) descoberta e sua fisiopatologia elaborada como resultante de deficiência secundária de cobre. O excesso de zinco bloqueia a absorção do cobre ligando-se às moléculas de cobre através da metalotioneína intestinal. A ingestão oral de zinco em excesso da necessidade diária mínima (aproximadamente 15 mg / d) pode esgotar os estoques totais de cobre do corpo, mas este tratamento pode levar anos para surtir efeito. | |||
| description / en | description / en | ||
Zinc-induced myeloneuropathy was recently (re)discovered and its pathophysiology elaborated as resulting from secondary copper deficiency. Excess zinc blocks copper absorption by binding to copper molecules through intestinal metallothionein. Oral intake of zinc in excess of the minimum daily requirement (approximately 15 mg/d) can deplete total body copper stores, but this treatment may take years to show effect. | |||
Revision as of 16:38, 15 August 2026
Zinc-induced myeloneuropathy was recently (re)discovered and its pathophysiology elaborated as resulting from secondary copper deficiency. Excess zinc blocks copper absorption by binding to copper molecules through intestinal metallothionein. Oral intake of zinc in excess of the minimum daily requirement (approximately 15 mg/d) can deplete total body copper stores, but this treatment may take years to show effect.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_1935468582 |
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| English | Myelopathy due to excess of zinc |
Zinc-induced myeloneuropathy was recently (re)discovered and its pathophysiology elaborated as resulting from secondary copper deficiency. Excess zinc blocks copper absorption by binding to copper molecules through intestinal metallothionein. Oral intake of zinc in excess of the minimum daily requirement (approximately 15 mg/d) can deplete total body copper stores, but this treatment may take years to show effect. |
