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Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome is a rare pleiotropic autoinflammatory disorder of childhood, primarily affecting the joints and skin, characterised by pauciarticular, nonaxial, sometimes recurrent, sterile arthritis beginning in childhood; pyoderma gangrenosum; and severe cystic acne in adolescence and beyond.
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    Pyogenic arthritis - pyoderma gangrenosum - acne
    Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome is a rare pleiotropic autoinflammatory disorder of childhood, primarily affecting the joints and skin, characterised by pauciarticular, nonaxial, sometimes recurrent, sterile arthritis beginning in childhood; pyoderma gangrenosum; and severe cystic acne in adolescence and beyond.

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