Thymoma-associated myasthenia gravis (Q88649): Difference between revisions

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Em cerca de 15% dos pacientes com Miastenia Gravis positivos para receptor de acetilcolina (AChR), mais comum nas 4ª a 6ª décadas, a doença pode ser classificada como paraneoplásica, geralmente associada a um timoma. O timoma nos pacientes com MG é tão ou menos maligno do que aquele sem MG. Anticorpos antiestriatais, incluindo antitina, anti-receptor de rianodina (RyR) e anticorpos Kv1.4, são encontrados com mais frequência em MG associada a timoma. Na MG quinase muscular específica (MuSK), o timoma é raro, embora pequenos timomas tenham sido relatados.
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In about 15% of the Acetylcholine receptor (AChR) positive Myasthenia Gravis patients, most common in 4th to 6th decades, the disease can be classified as paraneoplastic, usually associated with a thymoma. Thymoma with MG is equally or less malignant than that without MG. Anti-striational antibodies including anti-titin, ryanodine receptor (RyR), and Kv1.4 antibodies are more frequently found in thymoma-associated MG. In Muscle-specific kinase (MuSK) MG thymoma is rare, albeit small thymomas have been reported.

Revision as of 14:58, 15 August 2026

In about 15% of the Acetylcholine receptor (AChR) positive Myasthenia Gravis patients, most common in 4th to 6th decades, the disease can be classified as paraneoplastic, usually associated with a thymoma. Thymoma with MG is equally or less malignant than that without MG. Anti-striational antibodies including anti-titin, ryanodine receptor (RyR), and Kv1.4 antibodies are more frequently found in thymoma-associated MG. In Muscle-specific kinase (MuSK) MG thymoma is rare, albeit small thymomas have been reported.
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    English
    Thymoma-associated myasthenia gravis
    In about 15% of the Acetylcholine receptor (AChR) positive Myasthenia Gravis patients, most common in 4th to 6th decades, the disease can be classified as paraneoplastic, usually associated with a thymoma. Thymoma with MG is equally or less malignant than that without MG. Anti-striational antibodies including anti-titin, ryanodine receptor (RyR), and Kv1.4 antibodies are more frequently found in thymoma-associated MG. In Muscle-specific kinase (MuSK) MG thymoma is rare, albeit small thymomas have been reported.

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