Adult linear IgA bullous dermatosis (Q86692): Difference between revisions
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Dermatose bolhosa por IgA linear do adulto é uma doença autoimune da pele caracterizada por bolhas na pele e mucosas. As causas exatas da doença são desconhecidas, mas a doença é mediada por autoanticorpos IgA contra hemidesmossomas e componentes da membrana basal BP180 e seu ectodomínio shed, BP230 e LAD285. A doença afeta adultos de todas as idades, incluindo adultos jovens, mas é mais comum na velhice. Aqueles raros pacientes com envolvimento de mucosa muito proeminente com cicatrizes são agora classificados como penfigoide de membrana mucosa. | |||
| description / en | description / en | ||
Adult linear IgA bullous dermatosis is an autoimmune skin disease characterised by blisters on the skin and mucous membranes. The exact causes of the disease are unknown but the disease is mediated by IgA autoantibodies to hemidesmosome and basement membrane components BP180 and its shed ectodomain, BP230 and LAD285. The disease affects adults of all ages including young adults but is most common in old age. Those rare patients with very prominent mucosal involvement with scarring are now classified as mucous membrane pemphigoid. | |||
Revision as of 12:08, 15 August 2026
Adult linear IgA bullous dermatosis is an autoimmune skin disease characterised by blisters on the skin and mucous membranes. The exact causes of the disease are unknown but the disease is mediated by IgA autoantibodies to hemidesmosome and basement membrane components BP180 and its shed ectodomain, BP230 and LAD285. The disease affects adults of all ages including young adults but is most common in old age. Those rare patients with very prominent mucosal involvement with scarring are now classified as mucous membrane pemphigoid.
| Language | Label | Description | Also known as |
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| default for all languages | ID_913864335 |
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| English | Adult linear IgA bullous dermatosis |
Adult linear IgA bullous dermatosis is an autoimmune skin disease characterised by blisters on the skin and mucous membranes. The exact causes of the disease are unknown but the disease is mediated by IgA autoantibodies to hemidesmosome and basement membrane components BP180 and its shed ectodomain, BP230 and LAD285. The disease affects adults of all ages including young adults but is most common in old age. Those rare patients with very prominent mucosal involvement with scarring are now classified as mucous membrane pemphigoid. |
