Bornavirus encephalitis (Q84989): Difference between revisions
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| description / pt-br | description / pt-br | ||
Doença subaguda a aguda e frequentemente fatal causada por infecção por um bornavírus como resultado de transbordamento zoonótico a partir de um reservatório animal. A encefalite de Bornavírus começa com sintomas/sinais inespecíficos (p.ex., fadiga grave, fraqueza, dor de cabeça, lentificação psicomotora) seguidos por funções locomotoras progressivamente comprometidas, tetraparesia, estupor e coma. Na maioria dos casos descritos, a doença leva à morte várias semanas após o início dos sintomas. As lesões são tipicamente caracterizadas como encefalite não purulenta. O período de incubação é desconhecido, mas considera-se que dure de semanas a meses. Os vírus responsáveis estão restritos principalmente ao sistema nervoso central, ausentes no sangue, e a disseminação viral por humanos não foi documentada. Não há evidências de transmissão natural de pessoa a pessoa, mas a transmissão iatrogênica por transplante de órgãos sólidos é possível. | |||
| description / en | description / en | ||
A subacute to acute and often fatal disease caused by infection with a bornavirus as a result of spill-over transmission from an animal reservoir. Bornavirus encephalitis begins with unspecific symptoms/signs (e.g., severe fatigue, weakness, headache, psychomotor slowing) followed by progressively impaired locomotor functions, tetraparesis, sopor, and coma. In most described cases the disease will lead to death several weeks after the onset of symptoms. Lesions are typically characterised as non-purulent encephalitis. The incubation period is unknown but considered to last weeks to months. The etiologic viruses are restricted mainly to the central nervous system, absent in blood, and viral shedding by humans has not been documented. There is no evidence of natural person-to-person transmission, but iatrogenic transmission by solid organ transplantation is possible. | |||
Revision as of 10:21, 15 August 2026
A subacute to acute and often fatal disease caused by infection with a bornavirus as a result of spill-over transmission from an animal reservoir. Bornavirus encephalitis begins with unspecific symptoms/signs (e.g., severe fatigue, weakness, headache, psychomotor slowing) followed by progressively impaired locomotor functions, tetraparesis, sopor, and coma. In most described cases the disease will lead to death several weeks after the onset of symptoms. Lesions are typically characterised as non-purulent encephalitis. The incubation period is unknown but considered to last weeks to months. The etiologic viruses are restricted mainly to the central nervous system, absent in blood, and viral shedding by humans has not been documented. There is no evidence of natural person-to-person transmission, but iatrogenic transmission by solid organ transplantation is possible.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_475104996 |
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| English | Bornavirus encephalitis |
A subacute to acute and often fatal disease caused by infection with a bornavirus as a result of spill-over transmission from an animal reservoir. Bornavirus encephalitis begins with unspecific symptoms/signs (e.g., severe fatigue, weakness, headache, psychomotor slowing) followed by progressively impaired locomotor functions, tetraparesis, sopor, and coma. In most described cases the disease will lead to death several weeks after the onset of symptoms. Lesions are typically characterised as non-purulent encephalitis. The incubation period is unknown but considered to last weeks to months. The etiologic viruses are restricted mainly to the central nervous system, absent in blood, and viral shedding by humans has not been documented. There is no evidence of natural person-to-person transmission, but iatrogenic transmission by solid organ transplantation is possible. |
