Autoimmune cerebellar degeneration or cerebellitis (Q84136): Difference between revisions
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A degeneração cerebelar autoimune é um distúrbio inflamatório do cerebelo que tipicamente se manifesta de forma subaguda com sintomas (desequilíbrio e descoordenação) e sinais (por exemplo, ataxia) relacionados ao cerebelo. A cerebelite geralmente ocorre em crianças e pode ser decorrente de infecção primária, um processo autoimune pós-infeccioso ou pós-vacinal. A ressonância magnética pode mostrar aumento da folia dentro de um cerebelo aumentado e um líquido cefalorraquiano inflamatório é típico. Em adultos, a degeneração cerebelar autoimune é semelhante à degeneração cerebelar paraneoplásica [ver definição], mas não está relacionada ao câncer. Podem ser encontrados autoanticorpos neurais acompanhantes (por exemplo, ácido glutâmico-descarboxilase-65). Também é importante excluir outras causas de ataxia (por exemplo, encefalopatia de Wernickes). | |||
| description / en | description / en | ||
Autoimmune cerebellar degeneration is an inflammatory disorder of the cerebellum which typically manifests subacutely with symptoms (imbalance and in-co-ordination) and signs (e.g. ataxia) referable to the cerebellum. Cerebellitis usually occurs in children and may be due to primary infection, a post-infectious autoimmune or post-vaccineal process. MRI may show enhancement of folia within an enlarged cerebellum and an inflammatory spinal fluid is typical. In adults autoimmune cerebellar degeneration is similar to paraneoplastic cerebellar degeneration [see definition] but unrelated to cancer. Accompanying neural autoantibodies may be found (e.g. glutamic-acid-decarboxylase-65). It is also important to exclude other causes of ataxia (e.g. Wernickes encephalopathy). | |||
Revision as of 09:29, 15 August 2026
Autoimmune cerebellar degeneration is an inflammatory disorder of the cerebellum which typically manifests subacutely with symptoms (imbalance and in-co-ordination) and signs (e.g. ataxia) referable to the cerebellum. Cerebellitis usually occurs in children and may be due to primary infection, a post-infectious autoimmune or post-vaccineal process. MRI may show enhancement of folia within an enlarged cerebellum and an inflammatory spinal fluid is typical. In adults autoimmune cerebellar degeneration is similar to paraneoplastic cerebellar degeneration [see definition] but unrelated to cancer. Accompanying neural autoantibodies may be found (e.g. glutamic-acid-decarboxylase-65). It is also important to exclude other causes of ataxia (e.g. Wernickes encephalopathy).
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_1649435857 |
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| English | Autoimmune cerebellar degeneration or cerebellitis |
Autoimmune cerebellar degeneration is an inflammatory disorder of the cerebellum which typically manifests subacutely with symptoms (imbalance and in-co-ordination) and signs (e.g. ataxia) referable to the cerebellum. Cerebellitis usually occurs in children and may be due to primary infection, a post-infectious autoimmune or post-vaccineal process. MRI may show enhancement of folia within an enlarged cerebellum and an inflammatory spinal fluid is typical. In adults autoimmune cerebellar degeneration is similar to paraneoplastic cerebellar degeneration [see definition] but unrelated to cancer. Accompanying neural autoantibodies may be found (e.g. glutamic-acid-decarboxylase-65). It is also important to exclude other causes of ataxia (e.g. Wernickes encephalopathy). |
