Neuromyelitis optica spectrum disorder (Q84133): Difference between revisions
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Os transtornos do espectro da neuromielite óptica (NMOSD) são distúrbios desmielinizantes inflamatórios do sistema nervoso central (SNC) que representam formas limitadas de neuromielite óptica (NMO) [ver definição de NMO] e não preenchem os critérios de diagnóstico de NMO de 2006, que requerem neurite óptica e transversa mielite. NMOSDs requerem a detecção de aquaporina-4 IgG. Exemplos de NMOSDs incluem AQP4-IgG acompanhando neurite óptica única / recorrente ou mielite transversal única / recorrente e tipicamente mielite longitudinalmente extensa (> 3 segmentos vertebrais). Os NMOSDs menos comuns incluem ataques de náuseas e vômitos graves de lesões de área postrema e lesões cerebrais (por exemplo, encefalopatia reversível posterior como síndrome ou encefalomielite disseminada aguda)._x000D_ _x000D_ Os autoanticorpos neurais associados incluem:_x000D_ _x000D_ AQP4-IgG (autoanticorpos aquaporina-4) | |||
| description / en | description / en | ||
Neuromyelitis Optica Spectrum Disorders (NMOSD) are inflammatory demyelinating disorders of the central nervous system (CNS) which represent limited forms of Neuromyelitis Optica (NMO) [see NMO definition] and do not fulfill the 2006 NMO diagnostic criteria which requires both optic neuritis and transverse myelitis. NMOSD’s require the detection of aquaporin-4 IgG. Examples of NMOSD’s include AQP4-IgG accompanying either single/recurrent optic neuritis or single/recurrent typically longitudinally extensive (> 3 vertebral segments) transverse myelitis. Less common NMOSD’s include attacks of severe nausea and vomiting from area postrema lesions and cerebral lesions (e.g. posterior reversible encephalopathy like syndrome or acute disseminated encephalomyelitis). Associated neural autoantibodies include: AQP4-IgG (aquaporin-4 autoantibodies) | |||
Revision as of 09:29, 15 August 2026
Neuromyelitis Optica Spectrum Disorders (NMOSD) are inflammatory demyelinating disorders of the central nervous system (CNS) which represent limited forms of Neuromyelitis Optica (NMO) [see NMO definition] and do not fulfill the 2006 NMO diagnostic criteria which requires both optic neuritis and transverse myelitis. NMOSD’s require the detection of aquaporin-4 IgG. Examples of NMOSD’s include AQP4-IgG accompanying either single/recurrent optic neuritis or single/recurrent typically longitudinally extensive (> 3 vertebral segments) transverse myelitis. Less common NMOSD’s include attacks of severe nausea and vomiting from area postrema lesions and cerebral lesions (e.g. posterior reversible encephalopathy like syndrome or acute disseminated encephalomyelitis). Associated neural autoantibodies include: AQP4-IgG (aquaporin-4 autoantibodies)
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_290333867 |
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| English | Neuromyelitis optica spectrum disorder |
Neuromyelitis Optica Spectrum Disorders (NMOSD) are inflammatory demyelinating disorders of the central nervous system (CNS) which represent limited forms of Neuromyelitis Optica (NMO) [see NMO definition] and do not fulfill the 2006 NMO diagnostic criteria which requires both optic neuritis and transverse myelitis. NMOSD’s require the detection of aquaporin-4 IgG. Examples of NMOSD’s include AQP4-IgG accompanying either single/recurrent optic neuritis or single/recurrent typically longitudinally extensive (> 3 vertebral segments) transverse myelitis. Less common NMOSD’s include attacks of severe nausea and vomiting from area postrema lesions and cerebral lesions (e.g. posterior reversible encephalopathy like syndrome or acute disseminated encephalomyelitis). Associated neural autoantibodies include: AQP4-IgG (aquaporin-4 autoantibodies) |
