Necrolytic migratory erythema (Q68430): Difference between revisions
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Eritema necrolítico migratório é uma dermatose rara intimamente associada a um tumor secretor de glucagon das células das ilhotas pancreáticas (glucagonoma) subjacente. Pode se apresentar clinicamente com diabetes mellitus de início recente, perda de peso e glossite. A pele e as mucosas são afetadas com manchas policíclicas eritematosas migratórias dolorosas ou placas com pústulas, vesículas ou bolhas superficiais. As lesões são tipicamente disseminadas, mas estão acentuadas em áreas intertriginosas, abdome inferior e partes proximais das extremidades inferiores. As lesões começam como pápulas eritematosas; coalescem em manchas ou placas; evoluem para vesículas, bolhas flácidas e pústulas; e, em seguida, tornam-se erodidas e crostosas. | |||
| description / en | description / en | ||
Necrolytic migratory erythema is a rare dermatosis closely associated with an underlying glucagon-secreting tumour of pancreatic islet cells (glucagonoma). It may present clinically with recent onset diabetes mellitus, weight loss and glossitis. Skin and mucous membranes are affected with painful migratory erythematous polycyclic patches or plaques with superficial pustules, vesicles, or bullae. The lesions are typically widespread, but they are accentuated in the intertriginous areas, lower abdomen, and proximal parts of the lower extremities. Lesions begin as erythematous papules; coalesce into patches or plaques; evolve into vesicles, flaccid bullae, and pustules; and then become eroded and crusted. | |||
Revision as of 16:20, 14 August 2026
Necrolytic migratory erythema is a rare dermatosis closely associated with an underlying glucagon-secreting tumour of pancreatic islet cells (glucagonoma). It may present clinically with recent onset diabetes mellitus, weight loss and glossitis. Skin and mucous membranes are affected with painful migratory erythematous polycyclic patches or plaques with superficial pustules, vesicles, or bullae. The lesions are typically widespread, but they are accentuated in the intertriginous areas, lower abdomen, and proximal parts of the lower extremities. Lesions begin as erythematous papules; coalesce into patches or plaques; evolve into vesicles, flaccid bullae, and pustules; and then become eroded and crusted.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_537557682 |
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| English | Necrolytic migratory erythema |
Necrolytic migratory erythema is a rare dermatosis closely associated with an underlying glucagon-secreting tumour of pancreatic islet cells (glucagonoma). It may present clinically with recent onset diabetes mellitus, weight loss and glossitis. Skin and mucous membranes are affected with painful migratory erythematous polycyclic patches or plaques with superficial pustules, vesicles, or bullae. The lesions are typically widespread, but they are accentuated in the intertriginous areas, lower abdomen, and proximal parts of the lower extremities. Lesions begin as erythematous papules; coalesce into patches or plaques; evolve into vesicles, flaccid bullae, and pustules; and then become eroded and crusted. |
