Pierre Robin syndrome (Q46699): Difference between revisions

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A síndrome de Pierre-Robin (ou sequência de Pierre-Robin) é caracterizada por tríade de anomalias morfológicas orofaciais que consiste em retrognatismo, glossoptose e fenda velopalatal mediana posterior. Essa condição é chamada de sequência porque a fenda palatina posterior é um defeito secundário associado a desenvolvimento mandibular anormal: a hipoplasia mandibular ocorrendo no início da gestação faz com que a língua seja mantida elevada na cavidade oral, impedindo a fusão das prateleiras palatinas.
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Pierre-Robin syndrome (or Pierre-Robin sequence) is characterised by triad of orofacial morphological anomalies consisting of retrognathism, glossoptosis and a posterior median velopalatal cleft. This condition is referred to as a sequence because the posterior cleft palate is a secondary defect associated with abnormal mandibular development: mandibular hypoplasia occurring early in gestation causes the tongue to be maintained high-up in the oral cavity, preventing fusion of the palatal shelves.

Revision as of 15:28, 13 August 2026

Pierre-Robin syndrome (or Pierre-Robin sequence) is characterised by triad of orofacial morphological anomalies consisting of retrognathism, glossoptosis and a posterior median velopalatal cleft. This condition is referred to as a sequence because the posterior cleft palate is a secondary defect associated with abnormal mandibular development: mandibular hypoplasia occurring early in gestation causes the tongue to be maintained high-up in the oral cavity, preventing fusion of the palatal shelves.
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    English
    Pierre Robin syndrome
    Pierre-Robin syndrome (or Pierre-Robin sequence) is characterised by triad of orofacial morphological anomalies consisting of retrognathism, glossoptosis and a posterior median velopalatal cleft. This condition is referred to as a sequence because the posterior cleft palate is a secondary defect associated with abnormal mandibular development: mandibular hypoplasia occurring early in gestation causes the tongue to be maintained high-up in the oral cavity, preventing fusion of the palatal shelves.

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