Xeroderma pigmentosum (Q46642): Difference between revisions

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Xeroderma pigmentoso (XP) é uma genodermatose rara caracterizada por extrema sensibilidade a alterações induzidas por ultravioleta (UV) na pele e nos olhos, e múltiplos cânceres de pele. É subdividido em 8 grupos de complementação, de acordo com o gene afetado: XPA a XPG e variante XP (XPV). A gravidade das manifestações clínicas e a idade de início são extremamente variáveis e dependem em parte da exposição à luz solar e do grupo de complementação.
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Xeroderma pigmentosum (XP) is a rare genodermatosis characterised by extreme sensitivity to ultraviolet (UV)-induced changes in the skin and eyes, and multiple skin cancers. It is subdivided into 8 complementation groups, according to the affected gene: XPA to XPG, and XP variant (XPV). The severity of the clinical manifestations and the age of onset are extremely variable and are in part dependent on exposure to sunlight and the complementation group.

Revision as of 15:22, 13 August 2026

Xeroderma pigmentosum (XP) is a rare genodermatosis characterised by extreme sensitivity to ultraviolet (UV)-induced changes in the skin and eyes, and multiple skin cancers. It is subdivided into 8 complementation groups, according to the affected gene: XPA to XPG, and XP variant (XPV). The severity of the clinical manifestations and the age of onset are extremely variable and are in part dependent on exposure to sunlight and the complementation group.
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    English
    Xeroderma pigmentosum
    Xeroderma pigmentosum (XP) is a rare genodermatosis characterised by extreme sensitivity to ultraviolet (UV)-induced changes in the skin and eyes, and multiple skin cancers. It is subdivided into 8 complementation groups, according to the affected gene: XPA to XPG, and XP variant (XPV). The severity of the clinical manifestations and the age of onset are extremely variable and are in part dependent on exposure to sunlight and the complementation group.

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