Necrotising enterocolitis of newborn (Q45911): Difference between revisions

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Doença fulminante de recém-nascidos em que há ulceração extensa da mucosa, formação de pseudomembrana, hemorragia submucosa e necrose geralmente do cólon direito, ceco, íleo terminal e apêndice (ENTEROCOLITE), possivelmente devido à isquemia intestinal perinatal e invasão bacteriana. Todo o cólon, intestino delgado, estômago e esôfago também podem ser afetados. A maioria dos bebês é prematura ou sofre de síndrome do desconforto respiratório, sepse ou hipóxia. Os sintomas (aparentes durante as primeiras semanas de vida) incluem distensão abdominal, vômitos biliosos e melena; pode haver apneia, letargia, instabilidade de temperatura, taquicardia, taquipneia e queda da pressão arterial. O transtorno pode progredir para perfuração e peritonite.
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This is a fulminating disease of neonates in which there is extensive mucosal ulceration, pseudomembrane formation, submucosal haemorrhage, and necrosis usually of the right colon, caecum, terminal ileum, and appendix (ENTEROCOLITIS), possibly due to perinatal intestinal ischemia and bacterial invasion. The entire colon, small intestine, stomach, and oesophagus may also be affected. Most infants are premature or suffer from respiratory distress syndrome, sepsis, or hypoxia. Symptoms (apparent during the first few weeks of life) include abdominal distension, bilious vomiting, and melaena; there may be apnoea, lethargy, temperature instability, tachycardia, tachypnoea, and a fall in blood pressure. The disorder may progress to perforation and peritonitis.

Revision as of 14:10, 13 August 2026

This is a fulminating disease of neonates in which there is extensive mucosal ulceration, pseudomembrane formation, submucosal haemorrhage, and necrosis usually of the right colon, caecum, terminal ileum, and appendix (ENTEROCOLITIS), possibly due to perinatal intestinal ischemia and bacterial invasion. The entire colon, small intestine, stomach, and oesophagus may also be affected. Most infants are premature or suffer from respiratory distress syndrome, sepsis, or hypoxia. Symptoms (apparent during the first few weeks of life) include abdominal distension, bilious vomiting, and melaena; there may be apnoea, lethargy, temperature instability, tachycardia, tachypnoea, and a fall in blood pressure. The disorder may progress to perforation and peritonitis.
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KB88
    English
    Necrotising enterocolitis of newborn
    This is a fulminating disease of neonates in which there is extensive mucosal ulceration, pseudomembrane formation, submucosal haemorrhage, and necrosis usually of the right colon, caecum, terminal ileum, and appendix (ENTEROCOLITIS), possibly due to perinatal intestinal ischemia and bacterial invasion. The entire colon, small intestine, stomach, and oesophagus may also be affected. Most infants are premature or suffer from respiratory distress syndrome, sepsis, or hypoxia. Symptoms (apparent during the first few weeks of life) include abdominal distension, bilious vomiting, and melaena; there may be apnoea, lethargy, temperature instability, tachycardia, tachypnoea, and a fall in blood pressure. The disorder may progress to perforation and peritonitis.

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