Diffuse mesangial sclerosis (Q44655): Difference between revisions

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A esclerose mesangial difusa é uma apresentação histológica caracterizada por espessamento difuso da membrana basal e aumento maciço das áreas mesangiais, levando à contração e esclerose do tufo capilar glomerular. Pode ser observada em crianças com síndrome nefrótica resistente a esteroides de início precoce devida a uma variedade de anormalidades genéticas, seja como uma doença renal isolada ou como parte de uma síndrome de múltiplos órgãos.
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Diffuse mesangial sclerosis is a histological appearance which is characterised by diffuse thickening of basement membrane and massive enlargement of mesangial areas leading to contraction and sclerosis of the glomerular capillary tuft. It may be seen in children with early onset steroid resistant nephrotic syndrome due to a variety of genetic abnormalities, either as an isolated renal disease or as part of a multi-organ syndrome.

Revision as of 12:13, 13 August 2026

Diffuse mesangial sclerosis is a histological appearance which is characterised by diffuse thickening of basement membrane and massive enlargement of mesangial areas leading to contraction and sclerosis of the glomerular capillary tuft. It may be seen in children with early onset steroid resistant nephrotic syndrome due to a variety of genetic abnormalities, either as an isolated renal disease or as part of a multi-organ syndrome.
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    Diffuse mesangial sclerosis
    Diffuse mesangial sclerosis is a histological appearance which is characterised by diffuse thickening of basement membrane and massive enlargement of mesangial areas leading to contraction and sclerosis of the glomerular capillary tuft. It may be seen in children with early onset steroid resistant nephrotic syndrome due to a variety of genetic abnormalities, either as an isolated renal disease or as part of a multi-organ syndrome.

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