Pretibial myxoedema (Q44180): Difference between revisions
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Mixedema pré-tibial é uma forma de mucinose cutânea difusa em que há acúmulo de glicosaminoglicanos em excesso, especialmente ácido hialurônico, em derme e subcutâneo. É mais comumente observado nas pernas (áreas pré-tibiais), mas ocorre em outras partes das extremidades inferiores. Manifesta-se como nódulos, placas ou nódulos violáceos ou acastanhados, firmes, não depressíveis, assimétricos, que tendem a coalescer para produzir extensas áreas de inderuação com aparência de "peau d'orange" (casca de laranja)._x000D_ Quase sempre está associado a tireoidite autoimune (doença de Graves) e pode estar associado a baqueteamento digital (acropaquia) e exoftalmia (doença ocular da tireoide). | |||
| description / en | description / en | ||
Pretibial myxoedema is a form of diffuse cutaneous mucinosis in which there is an accumulation of excess glycosaminoglycans, especially hyaluronic acid, in the dermis and subcutis. It is most commonly seen on the shins (pretibial areas) but does occur elsewhere on the lower extremities. It manifests as violaceous or brownish, firm, non-pitting, asymmetrical nodules or plaques or nodules which tend to coalesce to produce extensive areas of induration with a "peau d'orange" (orange peel) appearance. It is nearly always associated with autoimmune thyroiditis (Graves disease) and may be associated with finger clubbing (acropachy) and exophthalmos (thyroid eye disease). | |||
Revision as of 11:32, 13 August 2026
Pretibial myxoedema is a form of diffuse cutaneous mucinosis in which there is an accumulation of excess glycosaminoglycans, especially hyaluronic acid, in the dermis and subcutis. It is most commonly seen on the shins (pretibial areas) but does occur elsewhere on the lower extremities. It manifests as violaceous or brownish, firm, non-pitting, asymmetrical nodules or plaques or nodules which tend to coalesce to produce extensive areas of induration with a "peau d'orange" (orange peel) appearance. It is nearly always associated with autoimmune thyroiditis (Graves disease) and may be associated with finger clubbing (acropachy) and exophthalmos (thyroid eye disease).
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | EB90.10 |
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| English | Pretibial myxoedema |
Pretibial myxoedema is a form of diffuse cutaneous mucinosis in which there is an accumulation of excess glycosaminoglycans, especially hyaluronic acid, in the dermis and subcutis. It is most commonly seen on the shins (pretibial areas) but does occur elsewhere on the lower extremities. It manifests as violaceous or brownish, firm, non-pitting, asymmetrical nodules or plaques or nodules which tend to coalesce to produce extensive areas of induration with a "peau d'orange" (orange peel) appearance. It is nearly always associated with autoimmune thyroiditis (Graves disease) and may be associated with finger clubbing (acropachy) and exophthalmos (thyroid eye disease). |
