Eosinophilic cellulitis (Q44173): Difference between revisions
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A celulite eosinofílica (síndrome de Wells) é caracterizada por um quadro clínico particular que se assemelha à celulite e uma histologia típica com eosinofilia tecidual, edema e figuras de “chama” (aglomerados de eosinófilos e histiócitos ao redor de um núcleo de colágeno e detritos eosinofílicos). Pode afetar ambos os sexos, geralmente na vida adulta. Qualquer localização pode estar envolvida, com lesões únicas ou múltiplas e as recorrências são comuns. Inicialmente, as lesões são placas eritematosas pruriginosas com características que lembram urticária e celulite, mas formas bolhosas e nodulares também foram descritas. Pode surgir espontaneamente, mas vários medicamentos e infecções foram implicados. | |||
| description / en | description / en | ||
Eosinophilic cellulitis (Wells syndrome) is characterised by a distinctive clinical picture resembling cellulitis, and a typical histology with tissue eosinophilia, oedema and ‘flame’ figures (clusters of eosinophils and histiocytes around a core of collagen and eosinophilic debris). It can affect either sex, usually in adult life. Any site may be involved, with single or multiple lesions, and recurrences are common. Initially, the lesions are itchy erythematous plaques with features resembling both urticaria and cellulitis but bullous and nodular forms have also been described. It may arise spontaneously but a number of drugs and infections have been implicated. | |||
Revision as of 11:32, 13 August 2026
Eosinophilic cellulitis (Wells syndrome) is characterised by a distinctive clinical picture resembling cellulitis, and a typical histology with tissue eosinophilia, oedema and ‘flame’ figures (clusters of eosinophils and histiocytes around a core of collagen and eosinophilic debris). It can affect either sex, usually in adult life. Any site may be involved, with single or multiple lesions, and recurrences are common. Initially, the lesions are itchy erythematous plaques with features resembling both urticaria and cellulitis but bullous and nodular forms have also been described. It may arise spontaneously but a number of drugs and infections have been implicated.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | EB30 |
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| English | Eosinophilic cellulitis |
Eosinophilic cellulitis (Wells syndrome) is characterised by a distinctive clinical picture resembling cellulitis, and a typical histology with tissue eosinophilia, oedema and ‘flame’ figures (clusters of eosinophils and histiocytes around a core of collagen and eosinophilic debris). It can affect either sex, usually in adult life. Any site may be involved, with single or multiple lesions, and recurrences are common. Initially, the lesions are itchy erythematous plaques with features resembling both urticaria and cellulitis but bullous and nodular forms have also been described. It may arise spontaneously but a number of drugs and infections have been implicated. |
