Benign acanthosis nigricans (Q44099): Difference between revisions
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Acantose nigricans benigna é um espessamento e uma pigmentação acometendo predominantemente a pele flexural, especialmente em pescoço, axilas e virilhas. Acredita-se que seja devida a alta taxa de ligação de insulina a receptores do fator de crescimento semelhante à insulina, com resultante proliferação de queratinócitos. Está fortemente associada à resistência à insulina e à obesidade. O diabetes tipo 2 e a síndrome metabólica estão comumente associados. | |||
| description / en | description / en | ||
Benign acanthosis nigricans is a thickening and pigmentation affecting predominantly flexural skin, especially the neck, axillae and groins. It is thought to be due to high concentrations of insulin binding to insulin-like growth factor receptors, with resultant keratinocyte proliferation. It is strongly associated with insulin resistance and obesity. Type 2 diabetes and the metabolic syndrome are commonly associated. | |||
Revision as of 11:25, 13 August 2026
Benign acanthosis nigricans is a thickening and pigmentation affecting predominantly flexural skin, especially the neck, axillae and groins. It is thought to be due to high concentrations of insulin binding to insulin-like growth factor receptors, with resultant keratinocyte proliferation. It is strongly associated with insulin resistance and obesity. Type 2 diabetes and the metabolic syndrome are commonly associated.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ED51.00 |
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| English | Benign acanthosis nigricans |
Benign acanthosis nigricans is a thickening and pigmentation affecting predominantly flexural skin, especially the neck, axillae and groins. It is thought to be due to high concentrations of insulin binding to insulin-like growth factor receptors, with resultant keratinocyte proliferation. It is strongly associated with insulin resistance and obesity. Type 2 diabetes and the metabolic syndrome are commonly associated. |
