Palmoplantar pustulosis (Q43898): Difference between revisions
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A pustulose palmoplantar (PPP) é uma condição inflamatória crônica da pele caracterizada por pústulas estéreis nas palmas das mãos e plantas dos pés que surgem repetidamente ao longo de meses ou anos. As áreas afetadas tendem a ficar eritematosas e descamativas; fissuras podem se formar e muitas vezes são dolorosas. Está fortemente associado ao tabagismo. Está associada à psoríase em outras partes do corpo em até 24% dos pacientes, embora pareça ter um perfil genético distinto da psoríase vulgar. Os polimorfismos do gene do receptor da interleucina-36 estão fortemente associados à psoríase pustulosa generalizada e foram detectados em uma minoria de pacientes com PPP. | |||
| description / en | description / en | ||
Palmoplantar pustulosis (PPP) is a chronic inflammatory skin condition characterised by crops of sterile pustules on the palms and soles which erupt repeatedly over months or years. The affected areas tend to become red and scaly; cracks may form and these are often painful. It is strongly associated with smoking. It is associated with psoriasis elsewhere on the body in up to 24% of patients though appears to have a genetic profile distinct from psoriasis vulgaris. Interleukin-36 receptor gene polymorphisms are strongly associated with generalised pustular psoriasis and have been detected in a minority of patients with PPP. | |||
Revision as of 11:06, 13 August 2026
Palmoplantar pustulosis (PPP) is a chronic inflammatory skin condition characterised by crops of sterile pustules on the palms and soles which erupt repeatedly over months or years. The affected areas tend to become red and scaly; cracks may form and these are often painful. It is strongly associated with smoking. It is associated with psoriasis elsewhere on the body in up to 24% of patients though appears to have a genetic profile distinct from psoriasis vulgaris. Interleukin-36 receptor gene polymorphisms are strongly associated with generalised pustular psoriasis and have been detected in a minority of patients with PPP.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | EA90.42 |
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| English | Palmoplantar pustulosis |
Palmoplantar pustulosis (PPP) is a chronic inflammatory skin condition characterised by crops of sterile pustules on the palms and soles which erupt repeatedly over months or years. The affected areas tend to become red and scaly; cracks may form and these are often painful. It is strongly associated with smoking. It is associated with psoriasis elsewhere on the body in up to 24% of patients though appears to have a genetic profile distinct from psoriasis vulgaris. Interleukin-36 receptor gene polymorphisms are strongly associated with generalised pustular psoriasis and have been detected in a minority of patients with PPP. |
