Primary biliary cholangitis (Q43609): Difference between revisions
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A colangite biliar primária é caracterizada pela destruição progressiva e desaparecimento das células epiteliais do ducto biliar intralobular, levando à colestase (fosfatase alcalina e GGT {gamma glutamil transferase} elevadas) e, eventualmente, cirrose hepática e insuficiência hepática, geralmente associada à presença de anticorpos antimitocondriais circulantes e aumento dos níveis séricos de IgM. | |||
| description / en | description / en | ||
Primary biliary cholangitis is characterised by progressive destruction and disappearance of the intralobular bile duct epithelial cells leading to cholestasis (high alkaline phosphatase and GGT {gamma glutamyl transferase}) and eventually liver cirrhosis and liver failure, generally associated with the presence of circulating antimitochondrial antibodies and an increase of serum IgM levels. | |||
Revision as of 10:41, 13 August 2026
Primary biliary cholangitis is characterised by progressive destruction and disappearance of the intralobular bile duct epithelial cells leading to cholestasis (high alkaline phosphatase and GGT {gamma glutamyl transferase}) and eventually liver cirrhosis and liver failure, generally associated with the presence of circulating antimitochondrial antibodies and an increase of serum IgM levels.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | DB96.1 |
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| English | Primary biliary cholangitis |
Primary biliary cholangitis is characterised by progressive destruction and disappearance of the intralobular bile duct epithelial cells leading to cholestasis (high alkaline phosphatase and GGT {gamma glutamyl transferase}) and eventually liver cirrhosis and liver failure, generally associated with the presence of circulating antimitochondrial antibodies and an increase of serum IgM levels. |
