Orofacial granulomatosis (Q43158): Difference between revisions
From determinar.ia.br - Determine suas informações
Created a new Item |
Changed label, description and/or aliases in pt-br, en |
||
| description / pt-br | description / pt-br | ||
Granulomatose orofacial (GOF) é uma entidade clínico-patológica incomum caracterizada por linfedema persistente e/ou recorrente e fissuras de lábios e mucosa oral (esta última com aspecto de "pedras da calçada"), ulceração oral e presença, na biópsia, de granulomas não caseosos. GOF pode ser uma manifestação precoce da doença de Crohn, às vezes apresentando-se meses ou anos antes da doença intestinal. Alguns casos estão associados a infecções dentárias, sarcoidose, alergia alimentar ou alergia de contato. A queilite granulomatosa é uma forma de GOF restrita aos lábios. Raramente, a GOF pode estar associada a língua fissurada e a paralisia facial (síndrome de Melkersson-Rosenthal). | |||
| description / en | description / en | ||
Orofacial granulomatosis (OFG) is an uncommon clinicopathological entity characterised by persistent and/or recurrent lymphoedema and fissuring of the lips and oral mucosa (the latter resulting in a "cobblestone" appearance), oral ulceration and the presence on biopsy of non-caseating granulomas. OFG may be an early manifestation of Crohn disease, sometimes presenting months or years before bowel disease. Some cases are associated with dental infections, sarcoidosis, food allergy or contact allergy. Granulomatous cheilitis is a form of OFG confined to the lips. Rarely, OFG may be associated with fissured tongue and facial palsy (Melkersson-Rosenthal syndrome). | |||
Revision as of 10:01, 13 August 2026
Orofacial granulomatosis (OFG) is an uncommon clinicopathological entity characterised by persistent and/or recurrent lymphoedema and fissuring of the lips and oral mucosa (the latter resulting in a "cobblestone" appearance), oral ulceration and the presence on biopsy of non-caseating granulomas. OFG may be an early manifestation of Crohn disease, sometimes presenting months or years before bowel disease. Some cases are associated with dental infections, sarcoidosis, food allergy or contact allergy. Granulomatous cheilitis is a form of OFG confined to the lips. Rarely, OFG may be associated with fissured tongue and facial palsy (Melkersson-Rosenthal syndrome).
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | DA01.21 |
||
| English | Orofacial granulomatosis |
Orofacial granulomatosis (OFG) is an uncommon clinicopathological entity characterised by persistent and/or recurrent lymphoedema and fissuring of the lips and oral mucosa (the latter resulting in a "cobblestone" appearance), oral ulceration and the presence on biopsy of non-caseating granulomas. OFG may be an early manifestation of Crohn disease, sometimes presenting months or years before bowel disease. Some cases are associated with dental infections, sarcoidosis, food allergy or contact allergy. Granulomatous cheilitis is a form of OFG confined to the lips. Rarely, OFG may be associated with fissured tongue and facial palsy (Melkersson-Rosenthal syndrome). |
