Cholesterol atheroembolism (Q42590): Difference between revisions

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Oclusão embólica de pequenas artérias e arteríolas distais por cristais de colesterol liberados de placa aterosclerótica em artérias maiores mais centrais. A isquemia microvascular resultante é acompanhada por uma resposta inflamatória à presença de cristais de colesterol. Isso pode ocorrer espontaneamente ou como uma complicação de angiografia ou cirurgia vascular. Os órgãos mais comumente afetados incluem pele, rins, trato gastrointestinal e cérebro. Manifestações cutâneas, presentes na maioria dos casos, incluem livedo reticularis e necrose e ulceração isquêmicas focais; estas estão comumente associadas a lesão renal aguda.
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Embolic occlusion of distal small arteries and arterioles by cholesterol crystals released from atherosclerotic plaque in larger more central arteries. The resultant microvascular ischaemia is accompanied by an inflammatory response to the presence of cholesterol crystals. This may occur spontaneously or as a complication of angiography or vascular surgery. Organs most commonly affected include the skin, kidneys, gastrointestinal tract, and brain. Cutaneous manifestations, present in the majority of cases, include livedo reticularis and focal ischaemic necrosis and ulceration; these are commonly associated with acute kidney injury.

Revision as of 09:11, 13 August 2026

Embolic occlusion of distal small arteries and arterioles by cholesterol crystals released from atherosclerotic plaque in larger more central arteries. The resultant microvascular ischaemia is accompanied by an inflammatory response to the presence of cholesterol crystals. This may occur spontaneously or as a complication of angiography or vascular surgery. Organs most commonly affected include the skin, kidneys, gastrointestinal tract, and brain. Cutaneous manifestations, present in the majority of cases, include livedo reticularis and focal ischaemic necrosis and ulceration; these are commonly associated with acute kidney injury.
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BD53.4
    English
    Cholesterol atheroembolism
    Embolic occlusion of distal small arteries and arterioles by cholesterol crystals released from atherosclerotic plaque in larger more central arteries. The resultant microvascular ischaemia is accompanied by an inflammatory response to the presence of cholesterol crystals. This may occur spontaneously or as a complication of angiography or vascular surgery. Organs most commonly affected include the skin, kidneys, gastrointestinal tract, and brain. Cutaneous manifestations, present in the majority of cases, include livedo reticularis and focal ischaemic necrosis and ulceration; these are commonly associated with acute kidney injury.

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