Inclusion body myopathy (Q41418): Difference between revisions
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A miopatia por corpos de inclusão (MCI) é diferenciada da polimiosite (PM) e dermatomiosite (DM) com base nas características clínicas e histopatológicas. Um fenótipo clínico típico é caracterizado por início insidioso de fraqueza muscular ao longo de meses a anos, fraqueza muscular localizada predominantemente nos músculos da coxa e flexores dos dedos e resistência ao tratamento com glicocorticoides. As características histopatológicas típicas incluem inclusões sarcoplasmáticas e nucleares, e vacúolos com bordas. | |||
| description / en | description / en | ||
Inclusion body myopathy (IBM) is distinguished from polymyositis (PM) and dermatomyositis (DM) on the basis of clinical and histopathological features. A characteristic clinical phenotype is characterised by insidious onset of muscle weakness over months to years, muscle weakness localised predominantly in the thigh muscles and finger flexors, and resistance to glucocorticoid treatment. Typical histopathologic features include sarcoplasmic and nuclear inclusions and rimmed vacuoles. | |||
Revision as of 07:35, 13 August 2026
Inclusion body myopathy (IBM) is distinguished from polymyositis (PM) and dermatomyositis (DM) on the basis of clinical and histopathological features. A characteristic clinical phenotype is characterised by insidious onset of muscle weakness over months to years, muscle weakness localised predominantly in the thigh muscles and finger flexors, and resistance to glucocorticoid treatment. Typical histopathologic features include sarcoplasmic and nuclear inclusions and rimmed vacuoles.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 4A41.2 |
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| English | Inclusion body myopathy |
Inclusion body myopathy (IBM) is distinguished from polymyositis (PM) and dermatomyositis (DM) on the basis of clinical and histopathological features. A characteristic clinical phenotype is characterised by insidious onset of muscle weakness over months to years, muscle weakness localised predominantly in the thigh muscles and finger flexors, and resistance to glucocorticoid treatment. Typical histopathologic features include sarcoplasmic and nuclear inclusions and rimmed vacuoles. |
