Frontotemporal dementia (Q40233): Difference between revisions
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A demência frontotemporal (DFT) é um grupo de transtornos neurodegenerativos primários que afetam primariamente os lobos frontal e temporal. O início é tipicamente insidioso, com piora gradativa. Diversas variantes sindrômicas (algumas com uma base genética identificada ou caráter familiar) são descritas, que incluem apresentações com predominância de mudanças proeminentes de personalidade e comportamento (como disfunção executiva, apatia, deterioração da cognição social, comportamentos repetitivos, e mudanças de dieta), predominância de déficits de linguagem (que incluem formas semânticas, agramáticas/não fluentes e logopênicas), predominância de déficits relacionados ao movimento (paralisia supranuclear progressiva, degeneração corticobasal, atrofia de múltiplos sistemas, ou esclerose lateral amiotrófica), ou uma combinação desses déficits. A memória frequentemente permanece relativamente intacta, principalmente durante os estágios iniciais da doença. | |||
| description / en | description / en | ||
Frontotemporal dementia (FTD) is a group of primary neurodegenerative disorders primarily affecting the frontal and temporal lobes. Onset is typically insidious with a gradual and worsening course. Several syndromic variants (some with an identified genetic basis or familiality) are described that include presentations with predominantly marked personality and behavioral changes (such as executive dysfunction, apathy, deterioration of social cognition, repetitive behaviours, and dietary changes), predominantly language deficits (that include semantic, agrammatic/nonfluent, and logopenic forms), predominantly movement-related deficits (progressive supranuclear palsy, corticobasal degeneration, multiple systems atrophy, or amyotrophic lateral sclerosis), or a combination of these deficits. Memory function often remains relatively intact, particularly during the early stages of the disorder. | |||
Revision as of 05:57, 13 August 2026
Frontotemporal dementia (FTD) is a group of primary neurodegenerative disorders primarily affecting the frontal and temporal lobes. Onset is typically insidious with a gradual and worsening course. Several syndromic variants (some with an identified genetic basis or familiality) are described that include presentations with predominantly marked personality and behavioral changes (such as executive dysfunction, apathy, deterioration of social cognition, repetitive behaviours, and dietary changes), predominantly language deficits (that include semantic, agrammatic/nonfluent, and logopenic forms), predominantly movement-related deficits (progressive supranuclear palsy, corticobasal degeneration, multiple systems atrophy, or amyotrophic lateral sclerosis), or a combination of these deficits. Memory function often remains relatively intact, particularly during the early stages of the disorder.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 6D83 |
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| English | Frontotemporal dementia |
Frontotemporal dementia (FTD) is a group of primary neurodegenerative disorders primarily affecting the frontal and temporal lobes. Onset is typically insidious with a gradual and worsening course. Several syndromic variants (some with an identified genetic basis or familiality) are described that include presentations with predominantly marked personality and behavioral changes (such as executive dysfunction, apathy, deterioration of social cognition, repetitive behaviours, and dietary changes), predominantly language deficits (that include semantic, agrammatic/nonfluent, and logopenic forms), predominantly movement-related deficits (progressive supranuclear palsy, corticobasal degeneration, multiple systems atrophy, or amyotrophic lateral sclerosis), or a combination of these deficits. Memory function often remains relatively intact, particularly during the early stages of the disorder. |
