Hypervitaminosis A (Q39976): Difference between revisions
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Como a vitamina A é solúvel em gordura e pode ser armazenada, principalmente no fígado, o consumo rotineiro de grandes quantidades de vitamina A durante um período de tempo pode resultar em sintomas tóxicos, incluindo danos ao fígado, anormalidades ósseas e dores nas articulações, alopecia, dores de cabeça, vômitos e descamação da pele. A hipervitaminose A parece ser devida ao transporte e distribuição anormais de vitamina A e retinóides causados pela sobrecarga dos mecanismos de transporte do plasma. Doses únicas muito altas podem causar sintomas tóxicos agudos transitórios que podem incluir fontanelas salientes em bebês; dores de cabeça em crianças mais velhas e adultos; e vômitos, diarréia, perda de apetite e irritabilidade em todas as faixas etárias. Raramente ocorre toxicidade pela ingestão de fontes alimentares de vitamina A pré-formada. Quando isso ocorre, geralmente resulta do consumo muito frequente de produtos do fígado. | |||
| description / en | description / en | ||
Because vitamin A is fat soluble and can be stored, primarily in the liver, routine consumption of large amounts of vitamin A over a period of time can result in toxic symptoms, including liver damage, bone abnormalities and joint pain, alopecia, headaches, vomiting, and skin desquamation. Hypervitaminosis A appears to be due to abnormal transport and distribution of vitamin A and retinoids caused by overloading of the plasma transport mechanisms. Very high single doses can cause transient acute toxic symptoms that may include bulging fontanelles in infants; headaches in older children and adults; and vomiting, diarrhoea, loss of appetite, and irritability in all age groups. Rarely does toxicity occur from ingestion of food sources of preformed vitamin A. When this occurs, it usually results from very frequent consumption of liver products. | |||
Revision as of 05:36, 13 August 2026
Because vitamin A is fat soluble and can be stored, primarily in the liver, routine consumption of large amounts of vitamin A over a period of time can result in toxic symptoms, including liver damage, bone abnormalities and joint pain, alopecia, headaches, vomiting, and skin desquamation. Hypervitaminosis A appears to be due to abnormal transport and distribution of vitamin A and retinoids caused by overloading of the plasma transport mechanisms. Very high single doses can cause transient acute toxic symptoms that may include bulging fontanelles in infants; headaches in older children and adults; and vomiting, diarrhoea, loss of appetite, and irritability in all age groups. Rarely does toxicity occur from ingestion of food sources of preformed vitamin A. When this occurs, it usually results from very frequent consumption of liver products.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 5B90.0 |
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| English | Hypervitaminosis A |
Because vitamin A is fat soluble and can be stored, primarily in the liver, routine consumption of large amounts of vitamin A over a period of time can result in toxic symptoms, including liver damage, bone abnormalities and joint pain, alopecia, headaches, vomiting, and skin desquamation. Hypervitaminosis A appears to be due to abnormal transport and distribution of vitamin A and retinoids caused by overloading of the plasma transport mechanisms. Very high single doses can cause transient acute toxic symptoms that may include bulging fontanelles in infants; headaches in older children and adults; and vomiting, diarrhoea, loss of appetite, and irritability in all age groups. Rarely does toxicity occur from ingestion of food sources of preformed vitamin A. When this occurs, it usually results from very frequent consumption of liver products. |
