Pellagra (Q39920): Difference between revisions
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Pelagra é um transtorno potencialmente fatal devido à deficiência de niacina e é observada em indivíduos desnutridos, especialmente alcoólatras, assim como uma complicação da terapia com isoniazida. O diagnóstico é frequentemente esquecido ou atrasado. A pelagra se manifesta como diarreia, dermatite, demência, que geralmente aparecem nesta ordem. Os sintomas do trato gastrointestinal sempre precedem o envolvimento da pele, que se apresenta inicialmente com um eritema com bolhas semelhante a queimaduras de sol, geralmente afetando as superfícies dorsais das mãos, rosto, pescoço, braços e pés. Com o tempo, a pele torna-se mais espessa, escamosa e pigmentada. | |||
| description / en | description / en | ||
Pellagra is a potentially life-threatening disorder due to niacin deficiency and is observed in malnourished individuals, especially alcoholics, and as a complication of isoniazid therapy. The diagnosis is often overlooked or delayed. Pellagra manifests as diarrhoea, dermatitis, dementia, which usually appear in this order. Gastrointestinal tract symptoms always precede skin involvement, which presents initially with a sunburn-like blistering erythema, typically affecting the dorsal surfaces of the hands, face, neck, arms, and feet. With time the skin becomes thickened, scaly and pigmented. | |||
Revision as of 05:31, 13 August 2026
Pellagra is a potentially life-threatening disorder due to niacin deficiency and is observed in malnourished individuals, especially alcoholics, and as a complication of isoniazid therapy. The diagnosis is often overlooked or delayed. Pellagra manifests as diarrhoea, dermatitis, dementia, which usually appear in this order. Gastrointestinal tract symptoms always precede skin involvement, which presents initially with a sunburn-like blistering erythema, typically affecting the dorsal surfaces of the hands, face, neck, arms, and feet. With time the skin becomes thickened, scaly and pigmented.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 5B5C.0 |
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| English | Pellagra |
Pellagra is a potentially life-threatening disorder due to niacin deficiency and is observed in malnourished individuals, especially alcoholics, and as a complication of isoniazid therapy. The diagnosis is often overlooked or delayed. Pellagra manifests as diarrhoea, dermatitis, dementia, which usually appear in this order. Gastrointestinal tract symptoms always precede skin involvement, which presents initially with a sunburn-like blistering erythema, typically affecting the dorsal surfaces of the hands, face, neck, arms, and feet. With time the skin becomes thickened, scaly and pigmented. |
