Premature ovarian failure (Q39878): Difference between revisions

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Menopausa que ocorre espontaneamente antes dos 40 anos de idade, geralmente resultando em amenorréia secundária, embora algumas mulheres possam apresentar função ovárica intermitente e ovulação, com uma minoria concebendo e dando à luz uma gravidez. FOP corre principalmente sem uma causa conhecida, mas pode ser causado pelas seguintes condições: anormalidades cromossômicas numéricas e estruturais, pré-mutações do X frágil, transtornos autoimunes, radioterapia, quimioterapia, galactosemia e outros defeitos enzimáticos raros ou mutações. É subdividido em 4 categorias de acordo com a causa: congênita, adquirida, iatrogênica e desconhecida.
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Menopause occurring spontaneously before 40 years of age, generally resulting in secondary amenorrhea although some women may exhibit intermittent ovarian function and ovulation, with a minority conceiving and delivering a pregnancy. POF/POI occurs mostly without a known cause, but can be caused by the following conditions: numerical and structural chromosomal abnormalities, Fragile X (FMR1) premutations, autoimmune disorders, radiation therapy, chemotherapy, galactosemia, and other rare enzyme defects or mutations. To be subdivided in 4 categories according to cause: congenital, acquired, iatrogenic and unknown

Revision as of 05:27, 13 August 2026

Menopause occurring spontaneously before 40 years of age, generally resulting in secondary amenorrhea although some women may exhibit intermittent ovarian function and ovulation, with a minority conceiving and delivering a pregnancy. POF/POI occurs mostly without a known cause, but can be caused by the following conditions: numerical and structural chromosomal abnormalities, Fragile X (FMR1) premutations, autoimmune disorders, radiation therapy, chemotherapy, galactosemia, and other rare enzyme defects or mutations. To be subdivided in 4 categories according to cause: congenital, acquired, iatrogenic and unknown
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GA30.6
    English
    Premature ovarian failure
    Menopause occurring spontaneously before 40 years of age, generally resulting in secondary amenorrhea although some women may exhibit intermittent ovarian function and ovulation, with a minority conceiving and delivering a pregnancy. POF/POI occurs mostly without a known cause, but can be caused by the following conditions: numerical and structural chromosomal abnormalities, Fragile X (FMR1) premutations, autoimmune disorders, radiation therapy, chemotherapy, galactosemia, and other rare enzyme defects or mutations. To be subdivided in 4 categories according to cause: congenital, acquired, iatrogenic and unknown

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