Chronic eosinophilic leukaemia, not elsewhere classified (Q39450): Difference between revisions
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Neoplasia mieloproliferativa crônica caracterizada por eosinofilia persistente no sangue, medula óssea e tecidos periféricos. As lesões aos órgãos ocorrem como resultado da infiltração leucêmica ou liberação de citocinas, enzimas ou outras proteínas pelos eosinófilos. A leucemia eosinofílica crônica, não especificada de outra forma, exclui pacientes com um cromossomo Ph, gene de fusão BCR-ABL1 ou rearranjo de PDGFRA, PDGFRB ou FGFR1. | |||
| description / en | description / en | ||
A chronic myeloproliferative neoplasm characterised by persistent eosinophilia in the blood, bone marrow and peripheral tissues. Organ damage occurs as a result of leukaemic infiltration or the release of cytokines, enzymes or other proteins by the eosinophils. Chronic eosinophilic leukaemia, not otherwise specified excludes patients with a Ph chromosome, BCR-ABL1 fusion gene or rearrangement of PDGFRA, PDGFRB or FGFR1. | |||
Revision as of 04:52, 13 August 2026
A chronic myeloproliferative neoplasm characterised by persistent eosinophilia in the blood, bone marrow and peripheral tissues. Organ damage occurs as a result of leukaemic infiltration or the release of cytokines, enzymes or other proteins by the eosinophils. Chronic eosinophilic leukaemia, not otherwise specified excludes patients with a Ph chromosome, BCR-ABL1 fusion gene or rearrangement of PDGFRA, PDGFRB or FGFR1.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 2A20.3 |
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| English | Chronic eosinophilic leukaemia, not elsewhere classified |
A chronic myeloproliferative neoplasm characterised by persistent eosinophilia in the blood, bone marrow and peripheral tissues. Organ damage occurs as a result of leukaemic infiltration or the release of cytokines, enzymes or other proteins by the eosinophils. Chronic eosinophilic leukaemia, not otherwise specified excludes patients with a Ph chromosome, BCR-ABL1 fusion gene or rearrangement of PDGFRA, PDGFRB or FGFR1. |
