Vulvar Paget disease (Q39261): Difference between revisions

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Neoplasia maligna intraepitelial incomum de origem écrina ou apócrina, originada da vulva. Geralmente afeta mulheres na pós-menopausa. Em aproximadamente 10-20% dos casos, há um carcinoma anorretal ou urotelial associado ou um adenocarcinoma de apêndice cutâneo identificado. Apresenta-se como uma lesão eczematosa vermelha. Microscopicamente, é caracterizada pela presença das células típicas de Paget, que são células grandes e redondas com citoplasma abundante e núcleos proeminentes.
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An uncommon intraepithelial malignant neoplasm of eccrine or apocrine origin, arising from the vulva. It usually affects post-menopausal women. In approximately 10-20% of the cases there is an associated anorectal, or urothelial carcinoma or a skin appendage adenocarcinoma identified. It presents as a red, eczematous lesion. Microscopically, it is characterised by the presence of the typical Paget cells which are large, round cells with abundant cytoplasm and prominent nuclei.

Revision as of 04:36, 13 August 2026

An uncommon intraepithelial malignant neoplasm of eccrine or apocrine origin, arising from the vulva. It usually affects post-menopausal women. In approximately 10-20% of the cases there is an associated anorectal, or urothelial carcinoma or a skin appendage adenocarcinoma identified. It presents as a red, eczematous lesion. Microscopically, it is characterised by the presence of the typical Paget cells which are large, round cells with abundant cytoplasm and prominent nuclei.
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2E67.11
    English
    Vulvar Paget disease
    An uncommon intraepithelial malignant neoplasm of eccrine or apocrine origin, arising from the vulva. It usually affects post-menopausal women. In approximately 10-20% of the cases there is an associated anorectal, or urothelial carcinoma or a skin appendage adenocarcinoma identified. It presents as a red, eczematous lesion. Microscopically, it is characterised by the presence of the typical Paget cells which are large, round cells with abundant cytoplasm and prominent nuclei.

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