Lentigo maligna melanoma, primary (Q38814): Difference between revisions

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O melanoma lentigo maligno é uma forma de melanoma que ocorre dentro de um lentigo maligno quando as células neoplásicas não permanecem mais confinadas à epiderme (crescimento radial in situ), mas invadem a derme (crescimento vertical). O lentigo maligno do qual se origina pode sido uma mácula irregularmente pigmentada na pele exposta ao sol por muitos anos antes de sobrevir a invasão dérmica. A diferenciação clínica do lentigo maligno pode não ser possível nos estágios iniciais da invasão, mas à medida que o tumor progride, um espessamento focal ou nódulo dentro do lentigo maligno se torna aparente.
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Lentigo maligna malignant melanoma is a form of melanoma which occurs within a lentigo maligna when neoplastic cells no longer remain confined to the epidermis (in situ radial growth) but invade the dermis (vertical growth). The lentigo maligna from which it arises may have been present as an irregularly pigmented macule on sun-exposed skin for many years before dermal invasion supervenes. Clinical differentiation from lentigo maligna may not be possible in the early stages of invasion but as the tumour progresses a focal thickening or nodule within the lentigo maligna will become apparent.

Revision as of 04:02, 13 August 2026

Lentigo maligna malignant melanoma is a form of melanoma which occurs within a lentigo maligna when neoplastic cells no longer remain confined to the epidermis (in situ radial growth) but invade the dermis (vertical growth). The lentigo maligna from which it arises may have been present as an irregularly pigmented macule on sun-exposed skin for many years before dermal invasion supervenes. Clinical differentiation from lentigo maligna may not be possible in the early stages of invasion but as the tumour progresses a focal thickening or nodule within the lentigo maligna will become apparent.
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2C30.2
    English
    Lentigo maligna melanoma, primary
    Lentigo maligna malignant melanoma is a form of melanoma which occurs within a lentigo maligna when neoplastic cells no longer remain confined to the epidermis (in situ radial growth) but invade the dermis (vertical growth). The lentigo maligna from which it arises may have been present as an irregularly pigmented macule on sun-exposed skin for many years before dermal invasion supervenes. Clinical differentiation from lentigo maligna may not be possible in the early stages of invasion but as the tumour progresses a focal thickening or nodule within the lentigo maligna will become apparent.

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