Squamous cell carcinoma of oropharynx (Q38606): Difference between revisions

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Carcinoma de células escamosas originando-se da orofaringe. Afeta predominantemente adultos nas quinta e sexta décadas de vida e está associada ao uso de álcool e tabaco. O papilomavírus humano está presente em aproximadamente metade dos casos. É caracterizado por uma tendência de metástase precoce para os gânglios linfáticos. Quando o tumor é pequeno, os pacientes são frequentemente assintomáticos. O exame físico pode revelar lesões ou placas eritematosas ou brancas. A maioria dos pacientes apresenta doença localmente avançada. Sinais e sintomas incluem ulceração da mucosa, dor, sangramento, perda de peso, inchaço no pescoço e dificuldade para falar, mastigar e engolir. Os pacientes também podem apresentar linfonodos cervicais inchados, sem quaisquer sintomas de tumor orofaríngeo. Os fatores prognósticos mais significativos são o tamanho do tumor e o status dos linfonodos.
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A squamous cell carcinoma arising from the oropharynx. It predominantly affects adults in their fifth and sixth decades of life and is associated with alcohol and tobacco use. Human papillomavirus is present in approximately half of the cases. It is characterised by a tendency to metastasize early to the lymph nodes. When the tumour is small, patients are often asymptomatic. Physical examination may reveal erythematous or white lesions or plaques. The majority of patients present with locally advanced disease. Signs and symptoms include mucosal ulceration, pain, bleeding, weight loss, neck swelling, and difficulty speaking, chewing, and swallowing. Patients may also present with swollen neck lymph nodes without any symptoms from the oropharyngeal tumour. The most significant prognostic factors are the size of the tumour and the lymph nodes status.

Revision as of 03:44, 13 August 2026

A squamous cell carcinoma arising from the oropharynx. It predominantly affects adults in their fifth and sixth decades of life and is associated with alcohol and tobacco use. Human papillomavirus is present in approximately half of the cases. It is characterised by a tendency to metastasize early to the lymph nodes. When the tumour is small, patients are often asymptomatic. Physical examination may reveal erythematous or white lesions or plaques. The majority of patients present with locally advanced disease. Signs and symptoms include mucosal ulceration, pain, bleeding, weight loss, neck swelling, and difficulty speaking, chewing, and swallowing. Patients may also present with swollen neck lymph nodes without any symptoms from the oropharyngeal tumour. The most significant prognostic factors are the size of the tumour and the lymph nodes status.
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    English
    Squamous cell carcinoma of oropharynx
    A squamous cell carcinoma arising from the oropharynx. It predominantly affects adults in their fifth and sixth decades of life and is associated with alcohol and tobacco use. Human papillomavirus is present in approximately half of the cases. It is characterised by a tendency to metastasize early to the lymph nodes. When the tumour is small, patients are often asymptomatic. Physical examination may reveal erythematous or white lesions or plaques. The majority of patients present with locally advanced disease. Signs and symptoms include mucosal ulceration, pain, bleeding, weight loss, neck swelling, and difficulty speaking, chewing, and swallowing. Patients may also present with swollen neck lymph nodes without any symptoms from the oropharyngeal tumour. The most significant prognostic factors are the size of the tumour and the lymph nodes status.

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