Paraneoplastic myoclonus (Q100581): Difference between revisions

@@ description / pt-br / description / pt-br @@
+Mioclonia paraneoplásica pode ocorrer no contexto de um câncer sem opsoclônus e pode ser tanto um componente de uma apresentação neurológica multifocal (p.ex. na encefalopatia autoimune) quanto ocorrer isoladamente. Os espasmos mioclônicos podem ser focais ou em todo o corpo e podem ser confundidos com tremor. Autoanticorpos neuronais concomitantes podem ser encontrados (p.ex. IgG contra proteína mediadora de resposta à colapsina 5) e é apropriado rastrear de um câncer subjacente, mas também é importante excluir outras patologias potenciais (p.ex. mioclônus induzido por drogas). _x000D_ Autoanticorpos associados:_x000D_ AMPA-R (anticorpo contra receptor de ácido amino-3-hidroxi-5-metil-4-isoxazolepropiônico); anfifisina; ANNA-1 (anti-Hu) (autoanticorpo nuclear antineuronal tipo 1); ANNA-2 (anti-Ri) (autoanticorpo nuclear antineuronal tipo 2); ANNA-3 (autoanticorpo nuclear antineuronal tipo 3); CRMP5(anti-CV2) (proteína mediadora de resposta à colapsina 5); GABABR (autoanticorpos contra receptores GABA tipo B); Ma1; Ma2; mGluR5 (anticorpo contra receptor de glutamato metabotrópico tipo 5); NMDA-R (autoanticorpos contra receptor de N-metil-D-aspartato); PCA-2 (autoanticorpo citoplasmático contra células de Purkinje tipo 2); PCA-Tr (anticorpo contra células de Purkinje Tr);
@@ description / en / description / en @@
+Paraneoplastic myoclonus may occur in the setting of cancer without opsoclonus and be either a component of a multifocal neurological presentation (e.g. in autoimmune encephalopathy) or occur in isolation. The myoclonic jerks may be focal or whole body and may be mistaken for tremor. Accompanying neural autoantibodies may be found (e.g. collapsing response mediator protein 5-IgG) and screening for an underlying cancer is appropriate, but it is also important to exclude other potential etiologies (e.g. drug induced myoclonus).  Associated autoantibodies: AMPA-R (amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antibodies); amphiphysin; ANNA-1(anti-Hu) (antineuronal nuclear autoantibody type 1); ANNA-2(anti-Ri) (antineuronal nuclear autoantibody type 2); ANNA-3 (antineuronal nuclear autoantibody type 3); CRMP5(anti-CV2) (collapsin response mediator protein 5); GABABR (Gamma-aminobutyric-acid type-B autoantibodies); Ma1; Ma2; mGluR5 (metabotropic glutamate receptor antibody type 5); NMDA-R (N-methyl-D-aspartate receptor autoantibodies); PCA-2 (purkinje cell cytoplasmic autoantibody type 2); PCA-Tr (purkinje cell autoantibody-Tr);
@@ Property / Canonical URI @@
+https://id.who.int/icd/entity/1906394190
@@ Property / Canonical URI: https://id.who.int/icd/entity/1906394190 / rank @@
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@@ Property / CURIE @@
+CID11:ID_1906394190
@@ Property / CURIE: CID11:ID_1906394190 / rank @@
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+dki-india-ID_1906394190
@@ Property / Canary Token: dki-india-ID_1906394190 / rank @@
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+Concluído
@@ Property / Verification Status: Concluído / rank @@
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@@ Property / Knowledge Architect @@
+https://pauloleads.com.br/cases-publicos/
+Normal rank
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+August 2026Timestamp +2026-08-15T00:00:00Z
Timezone +00:00
Calendar Gregorian
Precision 1 day
Before 0
After 0
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++2026-08-15T00:00:00Z
-Timezone
++00:00
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+Gregorian
-Precision
+day
 Before
 After
@@ Property / Collection date: 15 August 2026 / rank @@
+Normal rank

Latest revision as of 17:18, 16 August 2026

Paraneoplastic myoclonus may occur in the setting of cancer without opsoclonus and be either a component of a multifocal neurological presentation (e.g. in autoimmune encephalopathy) or occur in isolation. The myoclonic jerks may be focal or whole body and may be mistaken for tremor. Accompanying neural autoantibodies may be found (e.g. collapsing response mediator protein 5-IgG) and screening for an underlying cancer is appropriate, but it is also important to exclude other potential etiologies (e.g. drug induced myoclonus). Associated autoantibodies: AMPA-R (amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antibodies); amphiphysin; ANNA-1(anti-Hu) (antineuronal nuclear autoantibody type 1); ANNA-2(anti-Ri) (antineuronal nuclear autoantibody type 2); ANNA-3 (antineuronal nuclear autoantibody type 3); CRMP5(anti-CV2) (collapsin response mediator protein 5); GABABR (Gamma-aminobutyric-acid type-B autoantibodies); Ma1; Ma2; mGluR5 (metabotropic glutamate receptor antibody type 5); NMDA-R (N-methyl-D-aspartate receptor autoantibodies); PCA-2 (purkinje cell cytoplasmic autoantibody type 2); PCA-Tr (purkinje cell autoantibody-Tr);

Language	Label	Description	Also known as
default for all languages	ID_1906394190
English	Paraneoplastic myoclonus	Paraneoplastic myoclonus may occur in the setting of cancer without opsoclonus and be either a component of a multifocal neurological presentation (e.g. in autoimmune encephalopathy) or occur in isolation. The myoclonic jerks may be focal or whole body and may be mistaken for tremor. Accompanying neural autoantibodies may be found (e.g. collapsing response mediator protein 5-IgG) and screening for an underlying cancer is appropriate, but it is also important to exclude other potential etiologies (e.g. drug induced myoclonus). Associated autoantibodies: AMPA-R (amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antibodies); amphiphysin; ANNA-1(anti-Hu) (antineuronal nuclear autoantibody type 1); ANNA-2(anti-Ri) (antineuronal nuclear autoantibody type 2); ANNA-3 (antineuronal nuclear autoantibody type 3); CRMP5(anti-CV2) (collapsin response mediator protein 5); GABABR (Gamma-aminobutyric-acid type-B autoantibodies); Ma1; Ma2; mGluR5 (metabotropic glutamate receptor antibody type 5); NMDA-R (N-methyl-D-aspartate receptor autoantibodies); PCA-2 (purkinje cell cytoplasmic autoantibody type 2); PCA-Tr (purkinje cell autoantibody-Tr);