POEMS syndrome (Q94853): Difference between revisions
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A síndrome POEMS é definida pela presença de uma neuropatia periférica (P), um transtorno de plasmócitos monoclonais (M) e outras características paraneoplásicas, das quais as mais comuns são organomegalia (O), endocrinopatia (E), alterações cutâneas (S), papiledema, edema, derrames, ascite e trombocitose. Virtualmente todos os pacientes terão pelo menos uma lesão óssea esclerótica ou doença de Castleman concomitante._x000D_ Os autoanticorpos neurais associados são: Imunoglobulina G ou Imunoglobulina A com cadeia leve lambda, fator de crescimento endotelial vascular (VEGF) aumentado. | |||||||||||||||
| description / en | description / en | ||||||||||||||
POEMS syndrome is defined by the presence of a peripheral neuropathy (P), a monoclonal plasma cell disorder (M), and other paraneoplastic features, the most common of which are organomegaly (O), endocrinopathy (E), skin changes (S), papilledema, edema, effusions, ascites, and thrombocytosis. Virtually all patients will have either at least one sclerotic bone lesion or concomitant Castleman disease. Associated neural autoantibodies are: Immunoglobulin G or Immunoglobulin A with lambda light chain, increased Vascular Endothelial Growth Factor (VEGF). | |||||||||||||||
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| Property / Canonical URI: https://id.who.int/icd/entity/1555299114 / rank | |||||||||||||||
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CID11:ID_1555299114 | |||||||||||||||
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dki-india-ID_1555299114 | |||||||||||||||
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| Property / Knowledge Architect: https://pauloleads.com.br/cases-publicos/ / rank | |||||||||||||||
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15 August 2026
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| Property / Collection date: 15 August 2026 / rank | |||||||||||||||
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Latest revision as of 10:23, 16 August 2026
POEMS syndrome is defined by the presence of a peripheral neuropathy (P), a monoclonal plasma cell disorder (M), and other paraneoplastic features, the most common of which are organomegaly (O), endocrinopathy (E), skin changes (S), papilledema, edema, effusions, ascites, and thrombocytosis. Virtually all patients will have either at least one sclerotic bone lesion or concomitant Castleman disease. Associated neural autoantibodies are: Immunoglobulin G or Immunoglobulin A with lambda light chain, increased Vascular Endothelial Growth Factor (VEGF).
| Language | Label | Description | Also known as |
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| default for all languages | ID_1555299114 |
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| English | POEMS syndrome |
POEMS syndrome is defined by the presence of a peripheral neuropathy (P), a monoclonal plasma cell disorder (M), and other paraneoplastic features, the most common of which are organomegaly (O), endocrinopathy (E), skin changes (S), papilledema, edema, effusions, ascites, and thrombocytosis. Virtually all patients will have either at least one sclerotic bone lesion or concomitant Castleman disease. Associated neural autoantibodies are: Immunoglobulin G or Immunoglobulin A with lambda light chain, increased Vascular Endothelial Growth Factor (VEGF). |
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CID11:ID_1555299114
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dki-india-ID_1555299114
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Concluído
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15 August 2026
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