Idiopathic non-specific interstitial pneumonia (Q91643): Difference between revisions
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Pneumonia intersticial não específica idiopática é um tipo de pneumonia intersticial idiopática (PII). A pneumonia intersticial não específica idiopática tem sido associada a várias condições médicas, embora um link causal não tenha sido identificado. Além disto, ela pode ser idiopática. O nome pneumonia intersticial não específica (PINE) se originou como uma categoria histopatológica reservada para casos em que a biópsia pulmonar cirúrgica não demonstrava um padrão claramente identificável. O padrão histopatológico de PINE é encontrado em uma grande variedade de doenças de causa conhecida (p.ex., pneumonite de hipersensibilidade, doenças relacionadas a drogas, síndrome da imunodeficiência adquirida [SIDA] e doenças colágeno-vasculares). Ainda, muitos pacientes diagnosticados com PINE idiopática preenchem critérios para a definição de casos de doença indiferenciada do tecido conjuntivo, sugerindo que a PINE idiopática poderia ser, na realidade, uma doença autoimune. Além disto, estima-se que 15 a 20% dos pacientes que se apresentam com DIP (doença pulmonar intersticial) crônica têm uma doença do tecido conjuntivo oculta ou desenvolvem subsequentemente um quadro claro de doença do tecido conjuntivo. Neste grupo particular de pacientes, a apresentação clínica inicial pode ser essencialmente indistinguível daquela de várias PII (especialmente PINE e PIU) | |||||||||||||||
| description / en | description / en | ||||||||||||||
Idiopathic nonspecific interstitial pneumonia is one type of idiopathic interstitial pneumonias (IIPs). Idiopathic nonspecific interstitial pneumonia has been associated with many medical conditions, although a causal link has not been identified. In addition, it may be idiopathic. Nonspecific Interstitial Pneumonia(NSIP) originated as a histopathologic categorization reserved for surgical lung biopsies not demonstrating a clearly identifiable pattern. The histopathologic pattern of NSIP is found in a wide variety of diseases of known cause (e.g., hypersensitivity pneumonitis, drug-related, acquired immunodeficiency syndrome [AIDS]–related, and collagen-vascular diseases). Moreover, many patients diagnosed with idiopathic NSIP meet the case definition of undifferentiated connective tissue disease, suggesting that idiopathic NSIP might actually be an autoimmune disease. In addition, it is estimated that up to 15% to 20% of patients who present with a chronic ILD either have an occult connective tissue disease or subsequently develop a clinically overt connective tissue disease. In this particular group of patients, the initial clinical presentation may be essentially indistinguishable from that of several IIPs (especially NSIP and UIP). | |||||||||||||||
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13 August 2026
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Latest revision as of 18:40, 15 August 2026
Idiopathic nonspecific interstitial pneumonia is one type of idiopathic interstitial pneumonias (IIPs). Idiopathic nonspecific interstitial pneumonia has been associated with many medical conditions, although a causal link has not been identified. In addition, it may be idiopathic. Nonspecific Interstitial Pneumonia(NSIP) originated as a histopathologic categorization reserved for surgical lung biopsies not demonstrating a clearly identifiable pattern. The histopathologic pattern of NSIP is found in a wide variety of diseases of known cause (e.g., hypersensitivity pneumonitis, drug-related, acquired immunodeficiency syndrome [AIDS]–related, and collagen-vascular diseases). Moreover, many patients diagnosed with idiopathic NSIP meet the case definition of undifferentiated connective tissue disease, suggesting that idiopathic NSIP might actually be an autoimmune disease. In addition, it is estimated that up to 15% to 20% of patients who present with a chronic ILD either have an occult connective tissue disease or subsequently develop a clinically overt connective tissue disease. In this particular group of patients, the initial clinical presentation may be essentially indistinguishable from that of several IIPs (especially NSIP and UIP).
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_1319771917 |
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| English | Idiopathic non-specific interstitial pneumonia |
Idiopathic nonspecific interstitial pneumonia is one type of idiopathic interstitial pneumonias (IIPs). Idiopathic nonspecific interstitial pneumonia has been associated with many medical conditions, although a causal link has not been identified. In addition, it may be idiopathic. Nonspecific Interstitial Pneumonia(NSIP) originated as a histopathologic categorization reserved for surgical lung biopsies not demonstrating a clearly identifiable pattern. The histopathologic pattern of NSIP is found in a wide variety of diseases of known cause (e.g., hypersensitivity pneumonitis, drug-related, acquired immunodeficiency syndrome [AIDS]–related, and collagen-vascular diseases). Moreover, many patients diagnosed with idiopathic NSIP meet the case definition of undifferentiated connective tissue disease, suggesting that idiopathic NSIP might actually be an autoimmune disease. In addition, it is estimated that up to 15% to 20% of patients who present with a chronic ILD either have an occult connective tissue disease or subsequently develop a clinically overt connective tissue disease. In this particular group of patients, the initial clinical presentation may be essentially indistinguishable from that of several IIPs (especially NSIP and UIP). |
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CID11:ID_1319771917
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dki-india-ID_1319771917
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Concluído
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13 August 2026
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