Late chronic graft-versus-host disease (Q88777): Difference between revisions

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Doença do enxerto-versus-hospedeiro (GVHD) crônica tardia usualmente se apresenta entre 150 e 300 dias após o transplante. Pode se desenvolver a partir da forma liquenoide crônica precoce da GVHD ou pode surgir como manifestação nova. É caracterizada por líquen escleroso disseminado ou por espessamento da pele semelhante à morfeia e poiquilodermia. Bolhas, erosões, alopecia, cicatrizes conjuntivais e, eventualmente, fibroses profundas com contraturas articulares podem ocorrer. O quadro pode ser acompanhado de fibrose de outros órgãos, incluindo pulmão e fígado. GVHD crônica tardia pode causar morbidade significativa, desfiguração e incapacidade.
description / endescription / en
 
Late chronic-graft-versus-host disease (GVHD) usually presents between 150 and 300 days after engraftment. It may develop from the early chronic lichenoid form of GVHD or may arise de novo. It is characterised by widespread lichen sclerosus or morphoea-like thickening of the skin and poikiloderma. Blisters, erosions, alopecia, conjunctival scarring and, eventually, deep fibrosis with joint contractures may occur. These may be accompanied by fibrosis of other organs including lung and liver. Late chronic GVHD can result in considerable morbidity, disfigurement and disability.
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Property / Canonical URI: https://id.who.int/icd/entity/643345953 / rank
 
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CID11:ID_643345953
Property / CURIE: CID11:ID_643345953 / rank
 
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dki-india-ID_643345953
Property / Canary Token: dki-india-ID_643345953 / rank
 
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Concluído
Property / Verification Status: Concluído / rank
 
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Property / Knowledge Architect
 
Property / Knowledge Architect: https://pauloleads.com.br/cases-publicos/ / rank
 
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13 August 2026
Timestamp+2026-08-13T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
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Property / Collection date: 13 August 2026 / rank
 
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Latest revision as of 15:10, 15 August 2026

Late chronic-graft-versus-host disease (GVHD) usually presents between 150 and 300 days after engraftment. It may develop from the early chronic lichenoid form of GVHD or may arise de novo. It is characterised by widespread lichen sclerosus or morphoea-like thickening of the skin and poikiloderma. Blisters, erosions, alopecia, conjunctival scarring and, eventually, deep fibrosis with joint contractures may occur. These may be accompanied by fibrosis of other organs including lung and liver. Late chronic GVHD can result in considerable morbidity, disfigurement and disability.
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ID_643345953
    English
    Late chronic graft-versus-host disease
    Late chronic-graft-versus-host disease (GVHD) usually presents between 150 and 300 days after engraftment. It may develop from the early chronic lichenoid form of GVHD or may arise de novo. It is characterised by widespread lichen sclerosus or morphoea-like thickening of the skin and poikiloderma. Blisters, erosions, alopecia, conjunctival scarring and, eventually, deep fibrosis with joint contractures may occur. These may be accompanied by fibrosis of other organs including lung and liver. Late chronic GVHD can result in considerable morbidity, disfigurement and disability.

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      CID11:ID_643345953
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      dki-india-ID_643345953
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      Concluído
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      13 August 2026
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