Paraneoplastic hyperexcitability syndrome with continuous muscle fibre activity (Q84061): Difference between revisions

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Latest revision as of 09:25, 15 August 2026

The autoimmune hyperexcitability syndrome with CMFA, is a rare neuromuscular syndrome characterised by muscle weakness, often myokymia, CMFA, at times a cramp and fasciculation syndrome and autonomic features. Paraesthesia and hyperhydrosis are also common. Also CNS symptoms can be associated in Morvan`s syndrome. It can appear both as an autoimmune- and a paraneoplastic disease. An association with thymoma exists. The disease is soften antibody mediated in particular with potassium channel antibodies ( VGKC) and the CASPR2 and less LGII subtype. It responds to symptomatic therapy and immune therapies.

Language	Label	Description	Also known as
default for all languages	ID_1599858362
English	Paraneoplastic hyperexcitability syndrome with continuous muscle fibre activity	The autoimmune hyperexcitability syndrome with CMFA, is a rare neuromuscular syndrome characterised by muscle weakness, often myokymia, CMFA, at times a cramp and fasciculation syndrome and autonomic features. Paraesthesia and hyperhydrosis are also common. Also CNS symptoms can be associated in Morvan`s syndrome. It can appear both as an autoimmune- and a paraneoplastic disease. An association with thymoma exists. The disease is soften antibody mediated in particular with potassium channel antibodies ( VGKC) and the CASPR2 and less LGII subtype. It responds to symptomatic therapy and immune therapies.