Paraneoplastic acanthosis nigricans (Q55179): Difference between revisions

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Latest revision as of 02:49, 14 August 2026

Paraneoplastic acanthosis nigricans is thought to be due to production by the associated malignant tumour of factors which stimulate epidermal keratinocyte and dermal fibroblast proliferation. It is most commonly linked to underlying gastro-intestinal malignancy. In a third of cases it precedes the diagnosis of cancer. In contrast with benign acanthosis nigricans it often involves the extremities (tripe palms) and oral cavity.

Language	Label	Description	Also known as
default for all languages	ID_915843260
English	Paraneoplastic acanthosis nigricans	Paraneoplastic acanthosis nigricans is thought to be due to production by the associated malignant tumour of factors which stimulate epidermal keratinocyte and dermal fibroblast proliferation. It is most commonly linked to underlying gastro-intestinal malignancy. In a third of cases it precedes the diagnosis of cancer. In contrast with benign acanthosis nigricans it often involves the extremities (tripe palms) and oral cavity.