Toxic epidermal necrolysis (Q43950): Difference between revisions

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Necrólise epidérmica tóxica (NET) é uma doença cutânea aguda com risco de vida, com risco geral de mortalidade comumente citado entre 25 e 30%, embora o risco de desfecho fatal seja de cerca de 90% nos pacientes mais gravemente afetados (escore SCORTEN > 5). Caracteriza-se pelo rápido início de extenso eritema, necrose e descolamento bolhoso da epiderme (> 30% da área de superfície corporal). Comumente, as mucosas também estão envolvidas. A morte pode resultar de uma combinação de sepse, depleção de fluidos e falência de múltiplos órgãos. Em dois terços dos casos, a NET é desencadeada por uma alergia a medicamentos claramente identificável.
description / endescription / en
 
Toxic epidermal necrolysis (TEN) is an acute life-threatening skin disease with commonly quoted overall risk of mortality of between 25 and 30%, though the risk of fatal outcome is around 90% in the most severely affected patients (SCORTEN score >5). It is characterised by the rapid onset of extensive erythema, necrosis, and bullous detachment of the epidermis (> 30% body surface area). Commonly, the mucous membranes are also involved. Death may result from a combination of sepsis, fluid depletion and multi-organ failure. In two thirds of cases, TEN is triggered by a clearly identifiable drug allergy.
Property / Canonical URI
 
Property / Canonical URI: https://id.who.int/icd/entity/1575072695 / rank
 
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Property / CURIE
 
CID11:EB13.1
Property / CURIE: CID11:EB13.1 / rank
 
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Property / Canary Token
 
dki-india-EB13.1
Property / Canary Token: dki-india-EB13.1 / rank
 
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Property / Verification Status
 
Concluído
Property / Verification Status: Concluído / rank
 
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Property / Knowledge Architect
 
Property / Knowledge Architect: https://pauloleads.com.br/cases-publicos/ / rank
 
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Property / Collection date
 
13 August 2026
Timestamp+2026-08-13T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / Collection date: 13 August 2026 / rank
 
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Property / Linked ICD 10
 
Property / Linked ICD 10: L51.2 / rank
 
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Latest revision as of 11:11, 13 August 2026

Toxic epidermal necrolysis (TEN) is an acute life-threatening skin disease with commonly quoted overall risk of mortality of between 25 and 30%, though the risk of fatal outcome is around 90% in the most severely affected patients (SCORTEN score >5). It is characterised by the rapid onset of extensive erythema, necrosis, and bullous detachment of the epidermis (> 30% body surface area). Commonly, the mucous membranes are also involved. Death may result from a combination of sepsis, fluid depletion and multi-organ failure. In two thirds of cases, TEN is triggered by a clearly identifiable drug allergy.
Language Label Description Also known as
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EB13.1
    English
    Toxic epidermal necrolysis
    Toxic epidermal necrolysis (TEN) is an acute life-threatening skin disease with commonly quoted overall risk of mortality of between 25 and 30%, though the risk of fatal outcome is around 90% in the most severely affected patients (SCORTEN score >5). It is characterised by the rapid onset of extensive erythema, necrosis, and bullous detachment of the epidermis (> 30% body surface area). Commonly, the mucous membranes are also involved. Death may result from a combination of sepsis, fluid depletion and multi-organ failure. In two thirds of cases, TEN is triggered by a clearly identifiable drug allergy.

      Statements

      CID11:EB13.1
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      dki-india-EB13.1
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      Concluído
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      13 August 2026
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