Orofacial granulomatosis (Q43158): Difference between revisions

@@ description / pt-br / description / pt-br @@
+Granulomatose orofacial (GOF) é uma entidade clínico-patológica incomum caracterizada por linfedema persistente e/ou recorrente e fissuras de lábios e mucosa oral (esta última com aspecto de "pedras da calçada"), ulceração oral e presença, na biópsia, de granulomas não caseosos. GOF pode ser uma manifestação precoce da doença de Crohn, às vezes apresentando-se meses ou anos antes da doença intestinal. Alguns casos estão associados a infecções dentárias, sarcoidose, alergia alimentar ou alergia de contato. A queilite granulomatosa é uma forma de GOF restrita aos lábios. Raramente, a GOF pode estar associada a língua fissurada e a paralisia facial (síndrome de Melkersson-Rosenthal).
@@ description / en / description / en @@
+Orofacial granulomatosis (OFG) is an uncommon clinicopathological entity characterised by persistent and/or recurrent lymphoedema and fissuring of the lips and oral mucosa (the latter resulting in a "cobblestone" appearance), oral ulceration and the presence on biopsy of non-caseating granulomas. OFG may be an early manifestation of Crohn disease, sometimes presenting months or years before bowel disease. Some cases are associated with dental infections, sarcoidosis, food allergy or contact allergy. Granulomatous cheilitis is a form of OFG confined to the lips. Rarely, OFG may be associated with fissured tongue and facial palsy (Melkersson-Rosenthal syndrome).
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+https://id.who.int/icd/entity/239721777
@@ Property / Canonical URI: https://id.who.int/icd/entity/239721777 / rank @@
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@@ Property / CURIE @@
+CID11:DA01.21
@@ Property / CURIE: CID11:DA01.21 / rank @@
+Normal rank
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+dki-india-DA01.21
@@ Property / Canary Token: dki-india-DA01.21 / rank @@
+Normal rank
@@ Property / Verification Status @@
+Concluído
@@ Property / Verification Status: Concluído / rank @@
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@@ Property / Knowledge Architect @@
+https://pauloleads.com.br/cases-publicos/
+Normal rank
@@ Property / Collection date @@
+August 2026Timestamp +2026-08-13T00:00:00Z
Timezone +00:00
Calendar Gregorian
Precision 1 day
Before 0
After 0
-Timestamp
++2026-08-13T00:00:00Z
-Timezone
++00:00
-Calendar
+Gregorian
-Precision
+day
 Before
 After
@@ Property / Collection date: 13 August 2026 / rank @@
+Normal rank
@@ Property / Linked ICD 10 @@
+K13.4
@@ Property / Linked ICD 10: K13.4 / rank @@
+Normal rank

Latest revision as of 10:01, 13 August 2026

Orofacial granulomatosis (OFG) is an uncommon clinicopathological entity characterised by persistent and/or recurrent lymphoedema and fissuring of the lips and oral mucosa (the latter resulting in a "cobblestone" appearance), oral ulceration and the presence on biopsy of non-caseating granulomas. OFG may be an early manifestation of Crohn disease, sometimes presenting months or years before bowel disease. Some cases are associated with dental infections, sarcoidosis, food allergy or contact allergy. Granulomatous cheilitis is a form of OFG confined to the lips. Rarely, OFG may be associated with fissured tongue and facial palsy (Melkersson-Rosenthal syndrome).

Language	Label	Description	Also known as
default for all languages	DA01.21
English	Orofacial granulomatosis	Orofacial granulomatosis (OFG) is an uncommon clinicopathological entity characterised by persistent and/or recurrent lymphoedema and fissuring of the lips and oral mucosa (the latter resulting in a "cobblestone" appearance), oral ulceration and the presence on biopsy of non-caseating granulomas. OFG may be an early manifestation of Crohn disease, sometimes presenting months or years before bowel disease. Some cases are associated with dental infections, sarcoidosis, food allergy or contact allergy. Granulomatous cheilitis is a form of OFG confined to the lips. Rarely, OFG may be associated with fissured tongue and facial palsy (Melkersson-Rosenthal syndrome).