Diffuse panbronchiolitis (Q42853): Difference between revisions

@@ description / pt-br / description / pt-br @@
+Panbronquiolite difusa (PBD) é uma doença inflamatória idiopática que afeta principalmente os bronquíolos respiratórios, causando um transtorno respiratório obstrutivo grave progressivo de natureza supurativa. O início ocorre entre a segunda e quinta décadas da vida, e se manifesta com tosse crônica, dispneia ao esforço e produção de escarro. A maioria dos pacientes apresenta também sinusite crônica. Se não tratada, a PBD progride para bronquiectasias, insuficiência respiratória e morte. Melhora significativa do prognóstico foi relatada graças ao uso de antibióticos macrolídeos, cujo efeito é atribuído a uma ação anti-inflamatória e autorreguladora.
@@ description / en / description / en @@
+Diffuse panbronchiolitis (DPB) is an idiopathic inflammatory disease principally affecting the respiratory bronchioles, causing a progressive suppurative and severe obstructive respiratory disorder. Onset occurs in the second to fifth decade of life and manifests by chronic cough, exertional dyspnoea, and sputum production. Most patients also have chronic paranasal sinusitis. If left untreated, DPB progresses to bronchiectasis, respiratory failure and death. A significant improvement in the prognosis has been reported thanks to the use of long-term therapy with macrolide antibiotics, the effect of which is attributed to an anti-inflammatory and immunoregulatory action.
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+https://id.who.int/icd/entity/291357751
@@ Property / Canonical URI: https://id.who.int/icd/entity/291357751 / rank @@
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@@ Property / CURIE @@
+CID11:CA26.1
@@ Property / CURIE: CID11:CA26.1 / rank @@
+Normal rank
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+dki-india-CA26.1
@@ Property / Canary Token: dki-india-CA26.1 / rank @@
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@@ Property / Verification Status @@
+Concluído
@@ Property / Verification Status: Concluído / rank @@
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@@ Property / Knowledge Architect @@
+https://pauloleads.com.br/cases-publicos/
+Normal rank
@@ Property / Collection date @@
+August 2026Timestamp +2026-08-13T00:00:00Z
Timezone +00:00
Calendar Gregorian
Precision 1 day
Before 0
After 0
-Timestamp
++2026-08-13T00:00:00Z
-Timezone
++00:00
-Calendar
+Gregorian
-Precision
+day
 Before
 After
@@ Property / Collection date: 13 August 2026 / rank @@
+Normal rank
@@ Property / Linked ICD 10 @@
+J44.8
@@ Property / Linked ICD 10: J44.8 / rank @@
+Normal rank

Latest revision as of 09:34, 13 August 2026

Diffuse panbronchiolitis (DPB) is an idiopathic inflammatory disease principally affecting the respiratory bronchioles, causing a progressive suppurative and severe obstructive respiratory disorder. Onset occurs in the second to fifth decade of life and manifests by chronic cough, exertional dyspnoea, and sputum production. Most patients also have chronic paranasal sinusitis. If left untreated, DPB progresses to bronchiectasis, respiratory failure and death. A significant improvement in the prognosis has been reported thanks to the use of long-term therapy with macrolide antibiotics, the effect of which is attributed to an anti-inflammatory and immunoregulatory action.

Language	Label	Description	Also known as
default for all languages	CA26.1
English	Diffuse panbronchiolitis	Diffuse panbronchiolitis (DPB) is an idiopathic inflammatory disease principally affecting the respiratory bronchioles, causing a progressive suppurative and severe obstructive respiratory disorder. Onset occurs in the second to fifth decade of life and manifests by chronic cough, exertional dyspnoea, and sputum production. Most patients also have chronic paranasal sinusitis. If left untreated, DPB progresses to bronchiectasis, respiratory failure and death. A significant improvement in the prognosis has been reported thanks to the use of long-term therapy with macrolide antibiotics, the effect of which is attributed to an anti-inflammatory and immunoregulatory action.