Autoimmune myopathy (Q41407): Difference between revisions

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A miopatia autoimune é um subgrupo de miopatias inflamatórias idiopáticas que, apesar de terem diversas causas, apresentam as características histopatológicas comuns de necrose de miócitos sem inflamação significativa. Os pacientes apresentam uma miopatia proximal simétrica grave subaguda, associada a um nível de creatinoquinase acentuadamente elevado. Eles são mais provavelmente imunomediados, pois respondem à imunoterapia. É frequentemente acompanhada por terapia com estatinas, doenças do tecido conjuntivo, câncer e autoanticorpos específicos para partícula de reconhecimento de sinal (SRP) ou 3-hidroxi-3-metilglutaril-coenzima A redutase (HMGCR).
description / endescription / en
 
Autoimmune myopathy is a subgroup of idiopathic inflammatory myopathies, which, despite diverse causes, have the common histopathological features of myocyte necrosis without significant inflammation. Patients present with a subacute severe symmetrical proximal myopathy, associated with a markedly elevated creatine kinase level. These are most likely immune-mediated, as they respond to immunotherapy. It is often accompanied by statin therapy, connective tissue diseases, cancer, and autoantibodies specific for signal recognition particle (SRP) or 3-hydroxy-3-methylglutaryl–coenzyme A reductase (HMGCR).
Property / Canonical URI
 
Property / Canonical URI: https://id.who.int/icd/entity/1227790808 / rank
 
Normal rank
Property / CURIE
 
CID11:8C81
Property / CURIE: CID11:8C81 / rank
 
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Property / Canary Token
 
dki-india-8C81
Property / Canary Token: dki-india-8C81 / rank
 
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Property / Verification Status
 
Concluído
Property / Verification Status: Concluído / rank
 
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Property / Knowledge Architect
 
Property / Knowledge Architect: https://pauloleads.com.br/cases-publicos/ / rank
 
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Property / Collection date
 
13 August 2026
Timestamp+2026-08-13T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / Collection date: 13 August 2026 / rank
 
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Property / Linked ICD 10
 
Property / Linked ICD 10: G72 / rank
 
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Latest revision as of 07:34, 13 August 2026

Autoimmune myopathy is a subgroup of idiopathic inflammatory myopathies, which, despite diverse causes, have the common histopathological features of myocyte necrosis without significant inflammation. Patients present with a subacute severe symmetrical proximal myopathy, associated with a markedly elevated creatine kinase level. These are most likely immune-mediated, as they respond to immunotherapy. It is often accompanied by statin therapy, connective tissue diseases, cancer, and autoantibodies specific for signal recognition particle (SRP) or 3-hydroxy-3-methylglutaryl–coenzyme A reductase (HMGCR).
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8C81
    English
    Autoimmune myopathy
    Autoimmune myopathy is a subgroup of idiopathic inflammatory myopathies, which, despite diverse causes, have the common histopathological features of myocyte necrosis without significant inflammation. Patients present with a subacute severe symmetrical proximal myopathy, associated with a markedly elevated creatine kinase level. These are most likely immune-mediated, as they respond to immunotherapy. It is often accompanied by statin therapy, connective tissue diseases, cancer, and autoantibodies specific for signal recognition particle (SRP) or 3-hydroxy-3-methylglutaryl–coenzyme A reductase (HMGCR).

      Statements

      CID11:8C81
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      dki-india-8C81
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      Concluído
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      13 August 2026
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