AL amyloidosis (Q40143): Difference between revisions
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Amiloidose AL (amiloidose de cadeia leve) é devida à deposição de cadeias leves de imunoglobulina nos glomérulos, onde são vistas como fibrilas de ligação ao vermelho do Congo e imunocoradas especificamente para cadeias leves kappa ou lambda. À microscopia de luz, há material hialino amorfo no mesângio e nas paredes capilares. Um plasmócito produtor de cadeia leve ou uma displasia de células B é o responsável. Outros órgãos também estão envolvidos nessa doença sistêmica. | |||||||||||||||
| description / en | description / en | ||||||||||||||
AL (Amyloid Light-Chain) Amyloidosis is due to the deposition of immunoglobulin light chains in glomeruli where they are seen as Congo red binding fibrils and immuno-stain specifically for kappa or lambda light chains. By light microscopy there is amorphous hyaline material in the mesangium and capillary walls. A light chain producing plasma cell or B-cell dysplasia is responsible. Other organs are also involved in this systemic disease. | |||||||||||||||
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| Property / Canonical URI: https://id.who.int/icd/entity/1061366491 / rank | |||||||||||||||
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CID11:5D00.0 | |||||||||||||||
| Property / CURIE: CID11:5D00.0 / rank | |||||||||||||||
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dki-india-5D00.0 | |||||||||||||||
| Property / Canary Token: dki-india-5D00.0 / rank | |||||||||||||||
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Concluído | |||||||||||||||
| Property / Verification Status: Concluído / rank | |||||||||||||||
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| Property / Knowledge Architect: https://pauloleads.com.br/cases-publicos/ / rank | |||||||||||||||
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13 August 2026
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| Property / Collection date: 13 August 2026 / rank | |||||||||||||||
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| Property / Linked ICD 10: E85.8 / rank | |||||||||||||||
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Latest revision as of 05:50, 13 August 2026
AL (Amyloid Light-Chain) Amyloidosis is due to the deposition of immunoglobulin light chains in glomeruli where they are seen as Congo red binding fibrils and immuno-stain specifically for kappa or lambda light chains. By light microscopy there is amorphous hyaline material in the mesangium and capillary walls. A light chain producing plasma cell or B-cell dysplasia is responsible. Other organs are also involved in this systemic disease.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 5D00.0 |
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| English | AL amyloidosis |
AL (Amyloid Light-Chain) Amyloidosis is due to the deposition of immunoglobulin light chains in glomeruli where they are seen as Congo red binding fibrils and immuno-stain specifically for kappa or lambda light chains. By light microscopy there is amorphous hyaline material in the mesangium and capillary walls. A light chain producing plasma cell or B-cell dysplasia is responsible. Other organs are also involved in this systemic disease. |
Statements
CID11:5D00.0
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dki-india-5D00.0
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Concluído
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13 August 2026
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