Syndrome of inappropriate secretion of antidiuretic hormone (Q39843): Difference between revisions
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Síndrome da secreção inapropriada do hormônio antidiurético (ADH)- SIADH- é caracterizada pela secreção contínua de ADH causando hiponatremia, hiposmolalidade e natriurese. A prevelência exata é desconhecida. A doença tem sido descrita em grupos de todas as idades. SIADH é frequentemente associada a tumores, doenças pulmonares, transtornos do sistema nervoso central ou exposição a drogas. Ocasionalmente ela é encontrada em pacientes com insuficiência adrenal, tireoidiana ou hipofisária. O transtorno é causado por mutações com ganho de função em genes que codificam o receptor de vasopressina V2. Restrição hídrica é o tratamento mais comum. O resultado está relacionado aos distúrbios subjacentes e associados. | |||||||||||||||
| description / en | description / en | ||||||||||||||
Syndrome of inappropriate antidiuretic hormone (ADH) secretion (SIADH) is characterised by continued ADH secretion, leading to hyponatremia, hypoosmolality and natriuresis. Exact prevalence is unknown. The disease has been described in all age groups. SIADH is often associated with tumours, pulmonary disease, central nervous system disorders or exposure to drugs. Occasionally, it is found in patients with adrenal, thyroid or pituitary insufficiency. The disorder is caused by gain-of-function mutations in the gene encoding the vasopressin V2 receptor. Fluid restriction is the most common treatment. The outcome is related to the underlying and associated disorders. | |||||||||||||||
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| Property / Canonical URI: https://id.who.int/icd/entity/550787432 / rank | |||||||||||||||
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CID11:5A60.2 | |||||||||||||||
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dki-india-5A60.2 | |||||||||||||||
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| Property / Knowledge Architect: https://pauloleads.com.br/cases-publicos/ / rank | |||||||||||||||
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13 August 2026
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| Property / Collection date: 13 August 2026 / rank | |||||||||||||||
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| Property / Linked ICD 10: E22.2 / rank | |||||||||||||||
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Latest revision as of 05:24, 13 August 2026
Syndrome of inappropriate antidiuretic hormone (ADH) secretion (SIADH) is characterised by continued ADH secretion, leading to hyponatremia, hypoosmolality and natriuresis. Exact prevalence is unknown. The disease has been described in all age groups. SIADH is often associated with tumours, pulmonary disease, central nervous system disorders or exposure to drugs. Occasionally, it is found in patients with adrenal, thyroid or pituitary insufficiency. The disorder is caused by gain-of-function mutations in the gene encoding the vasopressin V2 receptor. Fluid restriction is the most common treatment. The outcome is related to the underlying and associated disorders.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 5A60.2 |
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| English | Syndrome of inappropriate secretion of antidiuretic hormone |
Syndrome of inappropriate antidiuretic hormone (ADH) secretion (SIADH) is characterised by continued ADH secretion, leading to hyponatremia, hypoosmolality and natriuresis. Exact prevalence is unknown. The disease has been described in all age groups. SIADH is often associated with tumours, pulmonary disease, central nervous system disorders or exposure to drugs. Occasionally, it is found in patients with adrenal, thyroid or pituitary insufficiency. The disorder is caused by gain-of-function mutations in the gene encoding the vasopressin V2 receptor. Fluid restriction is the most common treatment. The outcome is related to the underlying and associated disorders. |
Statements
CID11:5A60.2
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dki-india-5A60.2
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Concluído
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13 August 2026
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